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Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Stem Cells. Jan 26, 2015; 7(1): 106-115
Published online Jan 26, 2015. doi: 10.4252/wjsc.v7.i1.106
Advances in cellular technology in the hematology field: What have we learned so far?
Gustavo Torres de Souza, Claudinéia Pereira Maranduba, Camila Maurmann de Souza, Danielle Luciana Aurora Soares do Amaral, Francisco Carlos da Guia, Rafaella de Souza Salomão Zanette, João Vitor Paes Rettore, Natana Chaves Rabelo, Lucas Mendes Nascimento, Ícaro França Navarro Pinto, Júlia Boechat Farani, Abrahão Elias Hallack Neto, Fernando de Sá Silva, Carlos Magno da Costa Maranduba, Angelo Atalla
Gustavo Torres de Souza, Claudinéia Pereira Maranduba, Camila Maurmann de Souza, Danielle Luciana Aurora Soares do Amaral, Francisco Carlos da Guia, Rafaella de Souza Salomão Zanette, João Vitor Paes Rettore, Natana Chaves Rabelo, Fernando de Sá Silva, Carlos Magno da Costa Maranduba, Laboratory of Human Genetics and Cell Therapy, Biology Department, Biological Sciences Institute, Federal University of Juiz de Fora, Juiz de Fora 36036-900, Brazil
Lucas Mendes Nascimento, Ícaro França Navarro Pinto, Júlia Boechat Farani, Abrahão Elias Hallack Neto, Angelo Atalla, Haematology and Bone Marrow Transplantation Service, Medical Clinic Department, University Hospital, Federal University of Juiz de Fora, Juiz de Fora 36036-900, Brazil
Author contributions: All the authors contributed to this paper.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Angelo Atalla, PhD, Haematology and Bone Marrow Transplantation Service, Medical Clinic Department, University Hospital, Federal University of Juiz de Fora, R José Lourenço Kelmer-Martelos, Juiz de Fora 36036-900, Brazil. angeloatalla@yahoo.com
Telephone: +55-32-40095100
Received: July 25, 2014
Peer-review started: July 26, 2014
First decision: August 28, 2014
Revised: September 14, 2014
Accepted: September 18, 2014
Article in press: December 16, 2014
Published online: January 26, 2015
Processing time: 172 Days and 13.7 Hours
Core Tip

Core tip: In the past few years, considerable advance has been made possible in the field of cellular therapy, both in its basic and clinically applied form. Stem cells may have important future applications in hematology, with the possibility of supplying the blood needed for transfusion with the use of blood products produced in vitro. Thus, in this paper, we summarize the recently established protocols for differentiating both embryonic and induced pluripotent stem cells into blood cells for possible future use for hemotherapy.