Letter to the Editor
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Stem Cells. Oct 26, 2024; 16(10): 896-899
Published online Oct 26, 2024. doi: 10.4252/wjsc.v16.i10.896
Emergence of the stromal vascular fraction and secretome in regenerative medicine
Ratan Kumar Choudhary, Shanti Choudhary, Abhishek Tripathi
Ratan Kumar Choudhary, Shanti Choudhary, College of Animal Biotechnology, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana 141004, Punjab, India
Abhishek Tripathi, Hilltop Animal Hospital, Palatine, IL 60074, United States
Author contributions: Choudhary RK and Tripathi A conceived and drafted the editorial; Choudhary S provided critical revisions to the manuscript and was helpful in canine stromal vascular fraction work; All authors read and approved the final version of the manuscript.
Supported by the Department of Biotechnology, Ministry of Science and Technology, Government of India, New Delhi, No. BT/PR42179/AAQ/1/814/2021; and SERB-State University Research Excellence, No. SUR/2022/001952.
Conflict-of-interest statement: All authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ratan Kumar Choudhary, PhD, Assistant Professor, College of Animal Biotechnology, Guru Angad Dev Veterinary and Animal Sciences University, NH 95, Firozpur Road, Ludhiana 141004, Punjab, India. vetdrrkc@gmail.com
Received: August 8, 2024
Revised: September 24, 2024
Accepted: September 29, 2024
Published online: October 26, 2024
Processing time: 77 Days and 20.3 Hours
Core Tip

Core Tip: A recent mini-review highlighted critical steps for optimal stromal vascular fraction (SVF) isolation from adipose tissue, including liposuction refinement, tissue handling, enzymatic digestion, and rigorous quality control for cell viability and purity. This article expanded upon the review by examining the advantages and limitations of SVF isolation, exploring SVF isolation in canine patients, and discussing the future potential of SVF in regenerative medicine.