Enhanced wound healing and hemostasis with exosome-loaded gelatin sponges from human umbilical cord mesenchymal stem cells
Xin-Mei Hu, Can-Can Wang, Yu Xiao, Peng Jiang, Yu Liu, Zhong-Quan Qi, Medical College, Guangxi University, Nanning 530004, Guangxi Zhuang Autonomous Region, China
Author contributions: Qi ZQ and Hu XM contributed to the study conception and design; Hu XM, Wang CC, and Xiao Y contributed to data collection, analysis, and interpretation; Hu XM contributed to manuscript writing; Hu XM, Wang CC, Xiao Y, Jiang P, and Liu Y performed the animal experiments; Qi ZQ, Hu XM, and Xiao Y contributed to the conception, design, financial support, and final approval of the manuscript; and all the authors have read and approved the final manuscript.
Supported by the National Key R&D Program of China, No. 2018YFA0108304; the National Natural Science Foundation of China, No. 81771721 and 81971505; and the Innovation Project of Guangxi Graduate Education, No. YCBZ2022004 and YCBZ2022045.
Institutional animal care and use committee statement: All of the experimental procedures involving animals were reviewed and approved by the Ethics Committee of Guangxi University, Nanning, China (No. GXU-2021-1000).
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
ARRIVE guidelines statement: The authors have read the ARRIVE guidelines, and the manuscript was prepared and revised according to the ARRIVE guidelines.
: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Zhong-Quan Qi, MD, PhD, Professor, Medical College, Guangxi University, No. 100 Daxuedong Road, Nanning 530004, Guangxi Zhuang Autonomous Region, China. email@example.com
Received: August 14, 2023
Peer-review started: August 14, 2023
First decision: August 22, 2023
Revised: August 31, 2023
Accepted: September 14, 2023
Article in press: September 14, 2023
Published online: September 26, 2023