Retrospective Cohort Study
Copyright ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Oct 7, 2017; 23(37): 6877-6883
Published online Oct 7, 2017. doi: 10.3748/wjg.v23.i37.6877
Measurement of biological age may help to assess the risk of colorectal adenoma in screening colonoscopy
Sang-Jung Kim, Beom Jin Kim, Hyun Kang
Sang-Jung Kim, Department of Internal Medicine, Bundang Jesaeng Hospital, Sungnam-si, Gyungki-do 13590, South Korea
Beom Jin Kim, Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul 06973, South Korea
Hyun Kang, Department of Anesthesiology and Pain Medicine, Chung-Ang University College of Medicine, Seoul 06973, South Korea
Author contributions: Kim BJ designed research; Kim BJ and Kim SJ performed research; Kang H analyzed data; Kim SJ wrote the paper.
Institutional review board statement: This study protocol was approved by the Ethics Committees at Bundang Jesaeng Hospital (approval No. IMG 15-04).
Informed consent statement: Informed consent was waived by the IRB because the study used anonymous clinical data.
Conflict-of-interest statement: The authors declare no conflict of interest in this study.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Beom Jin Kim, MD, PhD, Associate Professor, Department of Internal Medicine, Chung-Ang University College of Medicine, 102 Heukseok-ro, Dongjak-gu, Seoul 06973, South Korea.
Telephone: +82-2-62992060 Fax: +82-2-62992064
Received: June 11, 2017
Peer-review started: June 12, 2017
First decision: July 13, 2017
Revised: August 15, 2017
Accepted: September 6, 2017
Article in press: September 5, 2017
Published online: October 7, 2017
Core Tip

Core tip: The present study was conducted on the basis of the hypothesis that colorectal adenoma recognized as a premalignant lesion of colorectal cancer is associated with the biological aging process, suggesting that biological age (BA) represents a biological activity in human. Thus, we intended to assess the risk of colorectal adenomas in the average-risk population from the biological perspective. As a result, the present study demonstrated that the prevalence of colorectal adenoma correlated well with BA, and was more common in the distal colon in BA -dominance.