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For: Liu ZQ, Zheng PY, Yang PC. Efflux pump gene hefA of Helicobacter pylori plays an important role in multidrug resistance. World J Gastroenterol 2008; 14(33): 5217-5222 [PMID: 18777600 DOI: 10.3748/wjg.14.5217]
URL: https://www.wjgnet.com/1007-9327/full/v14/i33/5217.htm
Number Citing Articles
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Sonia Agudo, Guillermo Pérez-Pérez, Teresa Alarcón, Manuel López-Brea. High Prevalence of Clarithromycin-Resistant Helicobacter pylori Strains and Risk Factors Associated with Resistance in Madrid, Spain Journal of Clinical Microbiology 2010; 48(10): 3703 doi: 10.1128/JCM.00144-10
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Jung Won Lee, Nayoung Kim, Jung Mogg Kim, Ryoung Hee Nam, Hyun Chang, Jae Yeon Kim, Cheol Min Shin, Young Soo Park, Dong Ho Lee, Hyun Chae Jung. Prevalence of Primary and Secondary Antimicrobial Resistance of Helicobacter pylori in Korea from 2003 through 2012Helicobacter 2013; 18(3): 206 doi: 10.1111/hel.12031
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Ilyas Alav, Jessica Kobylka, Miriam S. Kuth, Klaas M. Pos, Martin Picard, Jessica M. A. Blair, Vassiliy N. Bavro. Structure, Assembly, and Function of Tripartite Efflux and Type 1 Secretion Systems in Gram-Negative BacteriaChemical Reviews 2021; 121(9): 5479 doi: 10.1021/acs.chemrev.1c00055
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Hideo Yonezawa, Takako Osaki, Fuhito Hojo, Shigeru Kamiya. Effect of Helicobacter pylori biofilm formation on susceptibility to amoxicillin, metronidazole and clarithromycinMicrobial Pathogenesis 2019; 132: 100 doi: 10.1016/j.micpath.2019.04.030
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Josselin Bodilis, Olwen Simenel, Serge Michalet, Elisabeth Brothier, Thibault Meyer, Sabine Favre-Bonté, Sylvie Nazaret. HME, NFE, and HAE-1 efflux pumps in Gram-negative bacteria: a comprehensive phylogenetic and ecological approachISME Communications 2024; 4(1) doi: 10.1093/ismeco/ycad018
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Mercedes Figueroa, Armando Cortés, Álvaro Pazos, Luis Eduardo Bravo. Antimicrobial susceptibility of Helicobacter pylori with chronic gastritisBiomédica 2011; 32(1) doi: 10.7705/biomedica.v32i1.454
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Francis Megraud, Robin Bruyndonckx, Samuel Coenen, Linda Wittkop, Te-Din Huang, Martin Hoebeke, Lucie Bénéjat, Philippe Lehours, Herman Goossens, Youri Glupczynski. Helicobacter pyloriresistance to antibiotics in Europe in 2018 and its relationship to antibiotic consumption in the communityGut 2021; 70(10): 1815 doi: 10.1136/gutjnl-2021-324032
8
Jung Won Lee, Nayoung Kim, Ryoung Hee Nam, Ji Hyun Park, Yoon Jin Choi, Jung Mogg Kim, Joo Sung Kim, Hyun Chae Jung. GenoType HelicoDR test in the determination of antimicrobial resistance ofHelicobacter pyloriin KoreaScandinavian Journal of Gastroenterology 2014; 49(9): 1058 doi: 10.3109/00365521.2014.894117
9
Yifan Lin, Yongfu Shao, Jianing Yan, Guoliang Ye. Antibiotic resistance in Helicobacter pylori: From potential biomolecular mechanisms to clinical practiceJournal of Clinical Laboratory Analysis 2023; 37(7) doi: 10.1002/jcla.24885
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Jose Danilo Atehortua Rendon, Tania Liseth Pérez Cala, Alonso Martínez. Descripción de la resistencia de Helicobacter pylori a seis antibióticos de uso frecuente en ColombiaRevista Colombiana de Gastroenterología 2020; 35(3): 351 doi: 10.22516/25007440.493
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Alba A. Trespalacios, William Otero, Jorge E. Caminos, Marcela M. Mercado, Jenny Ávila, Liliana E. Rosero, Azucena Arévalo, Raúl A. Poutou-Piñales, David Y. Graham. Phenotypic and genotypic analysis of clarithromycin-resistant Helicobacter pylori from Bogotá D.C., ColombiaJournal of Microbiology 2013; 51(4): 448 doi: 10.1007/s12275-013-2465-6
12
Md Hasanuzzaman, Chang Seok Bang, Eun Jeong Gong. Antibiotic Resistance of Helicobacter pylori: Mechanisms and Clinical ImplicationsJournal of Korean Medical Science 2024; 39(4) doi: 10.3346/jkms.2024.39.e44
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Michele C. R. de Freitas, Juliana A. Resende, Alessandra B. Ferreira-Machado, Guadalupe D. R. Q. Saji, Ana T. R. de Vasconcelos, Vânia L. da Silva, Marisa F. Nicolás, Cláudio G. Diniz. Exploratory Investigation of Bacteroides fragilis Transcriptional Response during In vitro Exposure to Subinhibitory Concentration of MetronidazoleFrontiers in Microbiology 2016; 7 doi: 10.3389/fmicb.2016.01465
14
Nadia N. Qureshi, Brandon Gallaher, Neal L. Schiller. Evolution of Amoxicillin Resistance ofHelicobacter pyloriIn Vitro: Characterization of Resistance MechanismsMicrobial Drug Resistance 2014; 20(6): 509 doi: 10.1089/mdr.2014.0019
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Jennifer Li, Xian-Zhi Li. Efflux-Mediated Antimicrobial Resistance in Bacteria2016; : 489 doi: 10.1007/978-3-319-39658-3_19
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Nami Morales-Durán, Angel León-Buitimea, José R. Morones-Ramírez. Unraveling resistance mechanisms in combination therapy: A comprehensive review of recent advances and future directionsHeliyon 2024; 10(6): e27984 doi: 10.1016/j.heliyon.2024.e27984
17
Evariste Tshibangu-Kabamba, Patrick de Jesus Ngoma-Kisoko, Vo Phuoc Tuan, Takashi Matsumoto, Junko Akada, Yasutoshi Kido, Antoine Tshimpi-Wola, Pascal Tshiamala-Kashala, Steve Ahuka-Mundeke, Dieudonné Mumba Ngoy, Ghislain Disashi-Tumba, Yoshio Yamaoka. Next-Generation Sequencing of the Whole Bacterial Genome for Tracking Molecular Insight into the Broad-Spectrum Antimicrobial Resistance of Helicobacter pylori Clinical Isolates from the Democratic Republic of CongoMicroorganisms 2020; 8(6): 887 doi: 10.3390/microorganisms8060887
18
Bahgat Fayed, Jayalakshmi Jagal, Roberta Cagliani, Reena A. Kedia, Amr Elsherbeny, Hulya Bayraktutan, Ghalia Khoder, Mohamed Haider. Co-administration of amoxicillin-loaded chitosan nanoparticles and inulin: A novel strategy for mitigating antibiotic resistance and preserving microbiota balance in Helicobacter pylori treatmentInternational Journal of Biological Macromolecules 2023; 253: 126706 doi: 10.1016/j.ijbiomac.2023.126706
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Yuehua Gong, Yuan Yuan. Resistance mechanisms ofHelicobacter pyloriand its dual target precise therapyCritical Reviews in Microbiology 2018; 44(3): 371 doi: 10.1080/1040841X.2017.1418285
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Xiwen Geng, Wen Li, Zhenghong Chen, Sizhe Gao, Wei Hong, Xiaoran Ge, Guihua Hou, Zhekai Hu, Yabin Zhou, Beini Zeng, Wenjuan Li, Jihui Jia, Yundong Sun. The Bifunctional Enzyme SpoT Is Involved in the Clarithromycin Tolerance of Helicobacter pylori by Upregulating the Transporters HP0939, HP1017, HP0497, and HP0471Antimicrobial Agents and Chemotherapy 2017; 61(5) doi: 10.1128/AAC.02011-16
21
Xiaoran Ge, Yuying Cai, Zhenghong Chen, Sizhe Gao, Xiwen Geng, Ya Li, Yan Li, Jihui Jia, Yundong Sun. Bifunctional Enzyme SpoT Is Involved in Biofilm Formation of Helicobacter pylori with Multidrug Resistance by Upregulating Efflux Pump Hp1174 ( gluP ) Antimicrobial Agents and Chemotherapy 2018; 62(11) doi: 10.1128/AAC.00957-18
22
Anne Adebukola Adeyanju. Citrus Research - Horticultural and Human Health Aspects2023;  doi: 10.5772/intechopen.107903
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Xian-Zhi Li, Hiroshi Nikaido. Efflux-Mediated Drug Resistance in BacteriaDrugs 2009; 69(12): 1555 doi: 10.2165/11317030-000000000-00000
24
Elizabeth A. Trainor, Katherine E. Horton, Paul B. Savage, Traci L. Testerman, David J. McGee, B. A. McCormick. Role of the HefC Efflux Pump inHelicobacter pyloriCholesterol-Dependent Resistance to Ceragenins and Bile SaltsInfection and Immunity 2011; 79(1): 88 doi: 10.1128/IAI.00974-09
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Jung Won Lee. Helicobacter pylori2023; : 485 doi: 10.1007/978-981-97-0013-4_39
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Teng Xu, Fenfen Zhou, Li Wang, Shi Wu, Haihui Huang. Metronidazole-resistant Clostridioides difficile: genomic and transcriptomic traits acquired under in-vitro metronidazole inductionInternational Journal of Antimicrobial Agents 2022; 59(5): 106570 doi: 10.1016/j.ijantimicag.2022.106570
27
Shamshul Ansari, Yoshio Yamaoka. Helicobacter pylori Infection, Its Laboratory Diagnosis, and Antimicrobial Resistance: a Perspective of Clinical RelevanceClinical Microbiology Reviews 2022; 35(3) doi: 10.1128/cmr.00258-21
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Shu-Fang Ye, Jian-Mei Zhang, Fei Dai, Chen-Ju Lan, Xiao-Jun Zhang, Li-Zhen Zhou, Qing-Qing Tang, Fei Meng. Investigation of mutation of multidrug resistant Helicobacter pylori efflux pump gene based on whole genome sequencingWorld Chinese Journal of Digestology 2021; 29(9): 455 doi: 10.11569/wcjd.v29.i9.455
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29
Andrés González, Javier Casado, Ángel Lanas. Fighting the Antibiotic Crisis: Flavonoids as Promising Antibacterial Drugs Against Helicobacter pylori InfectionFrontiers in Cellular and Infection Microbiology 2021; 11 doi: 10.3389/fcimb.2021.709749
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Xiaoling Gong, Youhua Wang, Ying An, Zhen Li, Dongsheng Liu, Xie Yong. The crosstalk between efflux pump and resistance gene mutation in Helicobacter pylori Gut Microbes 2024; 16(1) doi: 10.1080/19490976.2024.2379439
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Giuseppe Zanotti, Laura Cendron. Helicobacter pylori in Human DiseasesAdvances in Experimental Medicine and Biology 2019; 1149: 227 doi: 10.1007/5584_2019_368
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Andreia T. Marques, Jorge M. B. Vítor, Andrea Santos, Mónica Oleastro, Filipa F. Vale. Trends in Helicobacter pylori resistance to clarithromycin: from phenotypic to genomic approaches Microbial Genomics 2020; 6(3) doi: 10.1099/mgen.0.000344
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Theodore Rokkas, Konstantinos Ekmektzoglou. Advances in the pharmacological and regulatory management of multidrug resistant Helicobacter pylori Expert Review of Clinical Pharmacology 2023; 16(12): 1229 doi: 10.1080/17512433.2023.2282061
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Yulong Zhang, Yingying Hou, Hui Ye, Xinjie Wang, Xuezhi Zhang, Jing Yu. Transcending antibiotic resistance: The potential of mass Galla chinensis et camelliae Fermentata to Dismantle Helicobacter pylori biofilms and enhance anti-biotic activityJournal of Ethnopharmacology 2024; 334: 118594 doi: 10.1016/j.jep.2024.118594
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Kartika Afrida Fauzia, Wiwin Is Effendi, Ricky Indra Alfaray, Hoda M. Malaty, Yoshio Yamaoka, Muhammad Mifthussurur. Molecular Mechanisms of Biofilm Formation in Helicobacter pyloriAntibiotics 2024; 13(10): 976 doi: 10.3390/antibiotics13100976
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Hiroshi Nikaido. RND transporters in the living worldResearch in Microbiology 2018; 169(7-8): 363 doi: 10.1016/j.resmic.2018.03.001
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Ilaria Maria Saracino, Matteo Pavoni, Angelo Zullo, Giulia Fiorini, Tiziana Lazzarotto, Claudio Borghi, Dino Vaira. Next Generation Sequencing for the Prediction of the Antibiotic Resistance in Helicobacter pylori: A Literature ReviewAntibiotics 2021; 10(4): 437 doi: 10.3390/antibiotics10040437
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Yan-Qiang Huang, Gan-Rong Huang, Ming-Hui Wu, Hua-Ying Tang, Zan-Song Huang, Xi-Han Zhou, Wen-Qiang Yu, Jian-Wei Su, Xiao-Qiang Mo, Bing-Pu Chen, Li-Juan Zhao, Xiao-Feng Huang, Hong-Yu Wei, Lian-Deng Wei. Inhibitory effects of emodin, baicalin, schizandrin and berberine on <italic>hefA</italic> gene: Treatment of <italic>Helicobacter pylori</italic>-induced multidrug resistanceWorld Journal of Gastroenterology 2015; 21(14): 4225-4231 doi: 10.3748/wjg.v21.i14.4225
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Yue Hu, Meng Zhang, Bin Lu, Jinfeng Dai. Helicobacter pylori and Antibiotic Resistance, A Continuing and Intractable ProblemHelicobacter 2016; 21(5): 349 doi: 10.1111/hel.12299
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Suthathip Kittisenachai, Panadda Rojpibulstit, Ratha-Korn Vilaichone, Pornpen Gamnarai, Narumon Phaonakrop, Nuchanart Suealek, Denise Monack. FBPAII and rpoBC, the Two Novel Secreted Proteins Identified by the Proteomic Approach from a Comparative Study between Antibiotic-Sensitive and Antibiotic-Resistant Helicobacter pylori-Associated Gastritis StrainsInfection and Immunity 2021; 89(6) doi: 10.1128/IAI.00053-21
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Jung Won Lee, Nayoung Kim, Ryoung Hee Nam, Sun Min Lee, Choi Soo In, Jung Mogg Kim, Dong Ho Lee. Risk factors of rescue bismuth quadruple therapy failure for Helicobacter pylori eradicationJournal of Gastroenterology and Hepatology 2019; 34(4): 666 doi: 10.1111/jgh.14625
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Natale Figura, Roberto Marcolongo, Giovanni Cavallo, Annalisa Santucci, Giulia Collodel, Adriano Spreafico, Elena Moretti. Polysorbate 80 and Helicobacter pylori: a microbiological and ultrastructural studyBMC Microbiology 2012; 12(1): 217 doi: 10.1186/1471-2180-12-217
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Hideo Yonezawa, Takako Osaki, Tomoko Hanawa, Satoshi Kurata, Kuniyasu Ochiai, Shigeru Kamiya, Qijing Zhang. Impact of Helicobacter pylori Biofilm Formation on Clarithromycin Susceptibility and Generation of Resistance MutationsPLoS ONE 2013; 8(9): e73301 doi: 10.1371/journal.pone.0073301
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Ricardo M Fernandes, Hélder Silva, Ricardo Oliveira, Carina Almeida, Nuno F Azevedo, Maria J Vieira. Morphological Transition of Helicobacter Pylori Adapted to Water Future Microbiology 2017; 12(13): 1167 doi: 10.2217/fmb-2016-0174
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Azucena Arévalo, William Alberto Otero, Alba Alicia Trespalacios. Helicobacter pylori: resistencia múltiple en pacientes de Bogotá, ColombiaBiomédica 2019; 39: 125 doi: 10.7705/biomedica.v39i3.4437
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Zeling Xu, Aixin Yan. Multidrug Efflux Systems in Microaerobic and Anaerobic BacteriaAntibiotics 2015; 4(3): 379 doi: 10.3390/antibiotics4030379
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Gerardo Zerbetto De Palma, Nicolas Mendiondo, Andrés Wonaga, Luis Viola, Daniela Ibarra, Esteban Campitelli, Nicolas Salim, Rodolfo Corti, Cinthia Goldman, Mariana Catalano. Occurrence of Mutations in the Antimicrobial Target Genes Related to Levofloxacin, Clarithromycin, and Amoxicillin Resistance inHelicobacter pyloriIsolates from Buenos Aires CityMicrobial Drug Resistance 2017; 23(3): 351 doi: 10.1089/mdr.2015.0361
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Surekha Challa, Titash Dutta, Pallaval Veera Bramhachari, Neelapu Nageswara Rao Reddy. Implication of Quorum Sensing and Biofilm Formation in Medicine, Agriculture and Food Industry2019; : 101 doi: 10.1007/978-981-32-9409-7_8
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Yuying Cai, Caixia Wang, Zhenghong Chen, Zhengzheng Xu, Huanjie Li, Wenjuan Li, Yundong Sun. Transporters HP0939, HP0497, and HP0471 participate in intrinsic multidrug resistance and biofilm formation in Helicobacter pylori by enhancing drug effluxHelicobacter 2020; 25(4) doi: 10.1111/hel.12715
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Chaille T. Webb, Dilini Chandrapala, Siti Nurbaya Oslan, Rebecca S. Bamert, Rhys D. Grinter, Rhys A. Dunstan, Rebecca J. Gorrell, Jiangning Song, Richard A. Strugnell, Trevor Lithgow, Terry Kwok. Reductive evolution in outer membrane protein biogenesis has not compromised cell surface complexity in Helicobacter pyloriMicrobiologyOpen 2017; 6(6) doi: 10.1002/mbo3.513
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Hitoshi Tsugawa, Hidekazu Suzuki, Hiroe Muraoka, Fumiaki Ikeda, Kenro Hirata, Juntaro Matsuzaki, Yoshimasa Saito, Toshifumi Hibi. Enhanced bacterial efflux system is the first step to the development of metronidazole resistance in Helicobacter pyloriBiochemical and Biophysical Research Communications 2011; 404(2): 656 doi: 10.1016/j.bbrc.2010.12.034
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Suvithan Rajadurai, Jonathan J. C. Ho, Erick A. Argueta, Yousef Elfanagely, Steven F. Moss. When and How Should Resistance Testing Be Performed to Improve H. pylori Eradication?Current Treatment Options in Gastroenterology 2023; 21(4): 447 doi: 10.1007/s11938-023-00436-y
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Jessy Peña, Héctor Rojas, Nelson Reyes, Milagro Fernández-Delgado, María-Alexandra García-Amado, Fabián Michelangeli, Monica Contreras. Multiple cag genotypes of Helicobacter pylori isolates colonize the oesophagus in individual hosts in a Venezuelan populationJournal of Medical Microbiology 2017; 66(2): 226 doi: 10.1099/jmm.0.000409
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Yong Hwan Kwon, Ji Yeon Kim, Nayoung Kim, Ji Hyun Park, Ryoung Hee Nam, Sun Min Lee, Jin‐Wook Kim, Jung Mogg Kim, Jong Youn Park, Dong Ho Lee. Specific mutations of penicillin‐binding protein 1A in 77 clinically acquired amoxicillin‐resistant Helicobacter pylori strains in comparison with 77 amoxicillin‐susceptible strainsHelicobacter 2017; 22(6) doi: 10.1111/hel.12437
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An N. T. Nguyen, Rebecca Gorrell, Terry Kwok, Tim Connallon, Michael J. McDonald. Horizontal gene transfer facilitates the molecular reverse-evolution of antibiotic sensitivity in experimental populations of H. pyloriNature Ecology & Evolution 2024; 8(2): 315 doi: 10.1038/s41559-023-02269-5
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Bahareh Attaran, Tahereh Falsafi, Nassim Ghorbanmehr. Effect of biofilm formation by clinical isolates of <i>Helicobacter pylori</i> on the efflux-mediated resistance to commonly used antibioticsWorld Journal of Gastroenterology 2017; 23(7): 1163-1170 doi: 10.3748/wjg.v23.i7.1163
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Xian-Zhi Li, Patrick Plésiat, Hiroshi Nikaido. The Challenge of Efflux-Mediated Antibiotic Resistance in Gram-Negative BacteriaClinical Microbiology Reviews 2015; 28(2): 337 doi: 10.1128/CMR.00117-14
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Muhammad Miftahussurur, Hafeza Aftab, Pradeep Krishna Shrestha, Rabi Prakash Sharma, Phawinee Subsomwong, Langgeng Agung Waskito, Dalla Doohan, Kartika Afrida Fauzia, Yoshio Yamaoka. Effective therapeutic regimens in two South Asian countries with high resistance to major Helicobacter pylori antibioticsAntimicrobial Resistance & Infection Control 2019; 8(1) doi: 10.1186/s13756-019-0482-x
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B. Akshaya Devi, Dhananjay Jade, K. H Sreenithya, Michael A. Harrison, Shobana Sugumar. Virtual screening, docking, molecular dynamics study of efflux pump inhibitors against Helicobacter pyloriChemical Papers 2024; 78(16): 8889 doi: 10.1007/s11696-024-03719-5
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Clara Belzer, Jeroen Stoof, Simone Breijer, Johannes G. Kusters, Ernst J. Kuipers, Arnoud H. M. Van Vliet. The Helicobacter hepaticus hefA Gene is Involved in Resistance to AmoxicillinHelicobacter 2009; 14(1): 72 doi: 10.1111/j.1523-5378.2009.00661.x
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Anastasia Dmitrieva, Oksana Kozlova, Victor Atuchin, Irina Milentieva, Anna Vesnina, Svetlana Ivanova, Lyudmila Asyakina, Alexander Prosekov. Study of the Effect of Baicalin from Scutellaria baicalensis on the Gastrointestinal Tract Normoflora and Helicobacter pyloriInternational Journal of Molecular Sciences 2023; 24(15): 11906 doi: 10.3390/ijms241511906
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Paweł Krzyżek. Helicobacter pylori Efflux Pumps: A Double-Edged Sword in Antibiotic Resistance and Biofilm FormationInternational Journal of Molecular Sciences 2024; 25(22): 12222 doi: 10.3390/ijms252212222
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Fansen Meng, Hongjin Tao, Yan Mi, Tianyu Yang, Xuanping Wang, Yuyo Go, Yunjuan Lin, Gangshi Wang. Nanocluster-mediated photothermia improves eradication efficiency and antibiotic sensitivity of Helicobacter pyloriCancer Nanotechnology 2022; 13(1) doi: 10.1186/s12645-022-00121-2
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Jung W. Lee, Nayoung Kim, Ryoung H. Nam, Ji H. Park, Jung M. Kim, Hyun C. Jung, In S. Song. Mutations of Helicobacter pylori Associated with Fluoroquinolone Resistance in KoreaHelicobacter 2011; 16(4): 301 doi: 10.1111/j.1523-5378.2011.00840.x
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Jung Won Lee. Helicobacter pylori2016; : 379 doi: 10.1007/978-981-287-706-2_36
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Cédric Bernarde, Philippe Lehours, Jean-Paul Lasserre, Michel Castroviejo, Marc Bonneu, Francis Mégraud, Armelle Ménard. Complexomics Study of Two Helicobacter pylori Strains of Two Pathological OriginsMolecular & Cellular Proteomics 2010; 9(12): 2796 doi: 10.1074/mcp.M110.001065
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Sun Min Lee, Nayoung Kim, Yong Hwan Kwon, Ryoung Hee Nam, Jung Mogg Kim, Jong Youn Park, Yeon Suk Lee, Dong Ho Lee. rdxA, frxA, and efflux pump in metronidazole‐resistant Helicobacter pylori: Their relation to clinical outcomesJournal of Gastroenterology and Hepatology 2018; 33(3): 681 doi: 10.1111/jgh.13906
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Vincenzo De Francesco, Angelo Zullo, Floriana Giorgio, Ilaria Saracino, Cristina Zaccaro, Cesare Hassan, Enzo Ierardi, Alfredo Di Leo, Giulia Fiorini, Valentina Castelli, Giovanna Lo Re, Dino Vaira. Change of point mutations in Helicobacter pylori rRNA associated with clarithromycin resistance in Italy Journal of Medical Microbiology 2014; 63(3): 453 doi: 10.1099/jmm.0.067942-0
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Camelia Quek, Son T. Pham, Kieu T. Tran, Binh T. Pham, Loc V. Huynh, Ngan B.L. Luu, Thao K.T. Le, Kelly Quek, Van H. Pham. Antimicrobial susceptibility and clarithromycin resistance patterns of Helicobacter pylori clinical isolates in VietnamF1000Research 2016; 5: 671 doi: 10.12688/f1000research.8239.1