Meta-Analysis
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Meta-Anal. Feb 28, 2021; 9(1): 88-100
Published online Feb 28, 2021. doi: 10.13105/wjma.v9.i1.88
Health-related quality of life in patients that have undergone liver resection: A systematic review and meta-analysis
Tomohiro Ishinuki, Shigenori Ota, Kohei Harada, Hiroomi Tatsumi, Keisuke Harada, Koji Miyanishi, Minoru Nagayama, Ichiro Takemasa, Toshio Ohyanagi, Thomas T Hui, Toru Mizuguchi
Tomohiro Ishinuki, Toru Mizuguchi, Department of Nursing, Surgical Sciences, Sapporo Medical University, Sapporo 060-8556, Japan
Shigenori Ota, Minoru Nagayama, Ichiro Takemasa, Departments of Surgery, Surgical Science and Oncology, Sapporo Medical University, Sapporo 060-8543, Japan
Kohei Harada, Division of Radiology, Sapporo Medical University, Sapporo 060-8543, Japan
Hiroomi Tatsumi, Department of Intensive Care Medicine, Sapporo Medical University Hospital, Sapporo 060-8543, Japan
Keisuke Harada, Department of Emergency Medicine, Sapporo Medical University Hospital, Sapporo 060-8543, Japan
Koji Miyanishi, Department of Medical Oncology, Sapporo Medical University Hospital, Sapporo 060-8543, Japan
Toshio Ohyanagi, Department of Liberal Arts and Sciences, Center for Medical Education, Sapporo Medical University, Sapporo 060-8556, Japan
Thomas T Hui, Department of Surgery, Division of Pediatric Surgery, Stanford University School of Medicine, Stanford, CA 94598, United States
Author contributions: Ishinuki T and Ota S conceptualized and designed the systematic review; Ishinuki T and Ohyagangi T searched for and screened the articles; Harada K and Tatsumi H assessed the articles for eligibility; Miyanaishi K and Nagayama M carried out the statistical analyses; Takemasa I supervised and audited the preparation of the manuscript; Hui TT and Mizuguchi T drafted the initial manuscript; Mizuguchi T finalized the manuscript; and all of the authors reviewed and approved the final manuscript as submitted.
Supported by Grant-in-Aid from JSPS KAKENHI, No. JP 20K10404 (to Mizuguchi T); the Hokkaido Hepatitis B Litigation Orange Fund, No. 2059198; Terumo Life Science Foundation, No. 2000666; Pfizer Health Research Foundation, No. 2000777; Daiichi Sankyo Company, No. 2109540; Shionogi and Co., No. 2109493; MSD, No. 2099412; Takeda, No, 2000555; Sapporo Doto Hospital, No. 2039118; Noguchi Hospital, No. 2029083; Doki-kai Tomakomai Hospital, No. 2059203; and Tsuchida Hospital, No. 2069231.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Toru Mizuguchi, MD, PhD, Professor, Surgeon, Department of Nursing, Surgical Sciences, Sapporo Medical University, S-1, W-16, Chuo-Ku, Sapporo 060-8556, Japan. tmizu@sapmed.ac.jp
Received: January 22, 2021
Peer-review started: January 22, 2021
First decision: February 10, 2021
Revised: February 10, 2021
Accepted: February 25, 2021
Article in press: February 25, 2021
Published online: February 28, 2021
Processing time: 39 Days and 10.2 Hours
Core Tip

Core Tip: A systematic review and meta-analysis of post-hepatectomy quality of life (QOL) assessments were conducted. A total of ten studies were included in the meta-analysis. QOL was better after hepatectomy than after transarterial chemoembolization. QOL was also better after laparoscopic hepatectomy than after open hepatectomy. The outcomes of post-hepatectomy QOL evaluations could depend on the type of questionnaire used, the timing of the assessment, and the etiology of the hepatic disease.