Published online Feb 28, 2021. doi: 10.13105/wjma.v9.i1.88
Peer-review started: January 22, 2021
First decision: February 10, 2021
Revised: February 10, 2021
Accepted: February 25, 2021
Article in press: February 25, 2021
Published online: February 28, 2021
Processing time: 39 Days and 10.2 Hours
Mortality after hepatectomy has decreased, and the quality of various surgical approaches to hepatectomy have been evaluated. Various assessments of quality of life (QOL) after hepatectomy have been developed and investigated in different clinical settings.
To conduct a systematic review and meta-analysis to examine two clinical topics: Laparoscopic hepatectomy vs open hepatectomy, and preoperative QOL status vs postoperative QOL status.
A systematic literature search was performed using PubMed and MEDLINE, including the Cochrane Library Central. The following inclusion criteria were set for inclusion in this meta-analysis: (1) Studies comparing preoperative QOL and postoperative QOL; and (2) Studies comparing QOL between laparoscopic hepatectomy and open hepatectomy.
A total of 8 articles were included in this meta-analysis. QOL was better after laparoscopic hepatectomy than after open hepatectomy.
The outcomes of evaluations of QOL after hepatectomy can depend on the type of questionnaire used, the timing of the assessment, and the etiology of the hepatic disease.
Core Tip: A systematic review and meta-analysis of post-hepatectomy quality of life (QOL) assessments were conducted. A total of ten studies were included in the meta-analysis. QOL was better after hepatectomy than after transarterial chemoembolization. QOL was also better after laparoscopic hepatectomy than after open hepatectomy. The outcomes of post-hepatectomy QOL evaluations could depend on the type of questionnaire used, the timing of the assessment, and the etiology of the hepatic disease.