Systematic Reviews
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Meta-Anal. Mar 18, 2025; 13(1): 100523
Published online Mar 18, 2025. doi: 10.13105/wjma.v13.i1.100523
Nutritional interventions in the treatment of Hashimoto’s disease: A systematic review
Carolina S Santos, Randhall B Carteri, Chaline Coghetto, Juliana Czermainski, Carolina B Rosa
Carolina S Santos, Randhall B Carteri, Chaline Coghetto, Carolina B Rosa, Department of Nutrition, Centro Universitário CESUCA, Cachoeirinha 94935-630, Brazil
Juliana Czermainski, Postgraduate Program in Hepatology, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre 90430-080, Brazil
Author contributions: Santos CS and Rosa CB were responsible for the conception and design, data collection, and manuscript writing; Rosa CB, Coghetto C, Czermainski J and Carteri RB were responsible for manuscript writing, and critical revision.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Randhall B Carteri, PhD, Postdoctoral Fellow, Professor, Department of Nutrition, Centro Universitário CESUCA, Silvério Manoel da Silva, 160- Colinas, Cachoeirinha 94935-630, Brazil. randhallcarteri@gmail.com
Received: August 19, 2024
Revised: November 13, 2024
Accepted: December 9, 2024
Published online: March 18, 2025
Processing time: 207 Days and 0.4 Hours
Core Tip

Core Tip: The review addresses the efficacy of different dietary approaches in treating Hashimoto’s thyroiditis (HT). Although gluten and lactose-free diets may benefit some patients, the evidence is controversial and varies according to individual sensitivity and other associated conditions. Paleo diets, which include lifestyle changes and micronutrient supplementation, have improved inflammatory and metabolic interventions in patients with HT. Nutritional interventions focused on anti-inflammatory diets and management of nutritional deficiencies are recommended as complementary alternatives to drug treatment.