Minimally invasive surgery vs laparotomy in patients with colon cancer residing in high-altitude areas

Table 1 Surgical conditions in the two groups (mean ± SD)

Group	Number of cases	Surgery duration (min)	Intraoperative blood loss (mL)	Gastrointestinal function recovery time (d)	Number of lymph node dissection
Minimally invasive group	46	189.39 ± 20.38	101.26 ± 18.64	2.55 ± 0.39	14.26 ± 3.15
Laparotomy group	46	145.62 ± 16.37	153.22 ± 23.39	3.37 ± 0.46	15.51 ± 3.49
t value		11.356	11.783	9.222	1.803
P value		0.000	0.000	0.000	0.075

Table 2 Inflammatory factors before and after surgery in the two groups (mean ± SD)

Time	Group	n	CRP (mg/L)	IL-6 (ng/mL)	TNF-α (pg/mL)
Before Surgery	Minimally invasive group	46	9.18 ± 3.38	122.33 ± 16.19	76.37 ± 11.25
	Laparotomy group	46	8.97 ± 3.60	119.64 ± 18.02	78.62 ± 13.18
	t value		0.288	0.753	0.881
	P value		0.774	0.453	0.381
After Surgery	Minimally invasive group	46	26.98 ± 6.91	146.38 ± 11.23	83.51 ± 8.69
	Laparotomy group	46	41.15 ± 8.39	186.79 ± 15.36	110.65 ± 12.84
	t value		8.842	14.404	11.872
	P value		0.000	0.000	0.000

CRP: C-reactive protein; IL-6: Interleukin-6; TNF-α: Tumor necrosis factor-α.

Table 3 Immune function indexes in the two groups before and after surgery (mean ± SD)

Time	Group	n	CD3+ (%)	CD4+ (%)	CD4+/CD8+
Before Surgery	Minimally invasive group	46	61.23 ± 6.45	40.26 ± 4.11	1.58 ± 0.50
	Laparotomy group	46	63.09 ± 5.96	39.64 ± 3.89	1.62 ± 0.44
	t value		1.436	0.743	0.407
	P value		0.154	0.459	0.685
After Surgery	Minimally invasive group	46	55.61 ± 4.39	35.45 ± 3.67	1.30 ± 0.35
	Laparotomy group	46	49.68 ± 5.33	31.21 ± 3.25	1.13 ± 0.30
	t value		5.825	5.866	2.501
	P value		0.000	0.000	0.014

Table 4 Complication probability in the two groups, n (%)

Group	n	Infection	Anastomotic leakage	Urinary retention	Intestinal obstruction	Total Incidence
Minimally invasive group	46	1 (2.17)	0 (0.00)	1 (2.17)	0 (0.00)	2 (4.35)
Laparotomy group	46	3 (6.52)	2 (4.35)	1 (2.17)	2 (4.35)	8 (17.39)
χ2 value						4.039
P value						0.044