Peng M, Yan QH, Gao Y, Zhang Z, Zhang Y, Wang YF, Wu HN. Correlation between circulating endothelial cell level and acute respiratory distress syndrome in postoperative patients. World J Clin Cases 2021; 9(32): 9731-9740 [PMID: 34877312 DOI: 10.12998/wjcc.v9.i32.9731]
Corresponding Author of This Article
Min Peng, MD, Chief Physician, Department of Intensive Care Unit, Tianjin Medical University General Hospital, No. 154 Anshan Street, Heping District, Tianjin 300070, China. pengmin2021@sina.com
Research Domain of This Article
Critical Care Medicine
Article-Type of This Article
Case Control Study
Open-Access Policy of This Article
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World J Clin Cases. Nov 16, 2021; 9(32): 9731-9740 Published online Nov 16, 2021. doi: 10.12998/wjcc.v9.i32.9731
Table 1 Clinical data of patients enrolled
Clinical data
n (%)
Gender
Male
75 (60)
Female
50 (40)
Age
Age distribution
33-67
Average
53 ± 11
Mechanical ventilation
105 (84)
ARDS occurrence
52 (42)
Improvement
39 (31)
Death
13 (10)
Average APACHE II score
11 ± 5
Department type
General surgery
77 (62)
Orthopedics
25 (20)
Other
23 (18)
Table 2 Comparison of the levels of circulating endothelial cells in three groups, mean ± SD
Group
Number
Count of CECs, in mL
ARDS Group
52
2064 ± 892
Non-ARDS Group
73
1038 ± 1371
Healthy control group
32
167 ± 148
Table 3 Comparison of day 2 circulating endothelial cells levels between death group and improvement group in acute respiratory distress syndrome patients, mean ± SD
Group
Number
Count of CECs, mL
P value
Deceased group
13
2863 ± 651
< 0.001
Improvement group
39
1799 ± 801
Table 4 Comparison of number of day 2 circulating endothelial cells in patients with acute respiratory distress syndrome under different severity, mean ± SD
Severity of ARDS
Number
Count of CECs, mL
Mild
19
1924 ± 872
Moderate
20
1897 ± 890
Severe
13
2580 ± 791
Table 5 Changes of circulating endothelial cells levels in three groups as acute respiratory distress syndrome development, mean ± SD
Group
Number
Count of CECs, mL
P value
Count of d2 CECs
Count of d5 CECs
Non-ARDS group
73
1038 ± 1371
854 ± 648
0.273
Improvement group
39
1799 ± 801
2274 ± 1017
< 0.001
Death group
13
2863 ± 652
3548 ± 1035
0.002
Citation: Peng M, Yan QH, Gao Y, Zhang Z, Zhang Y, Wang YF, Wu HN. Correlation between circulating endothelial cell level and acute respiratory distress syndrome in postoperative patients. World J Clin Cases 2021; 9(32): 9731-9740