Case Report
Copyright ©The Author(s) 2021.
World J Clin Cases. Oct 26, 2021; 9(30): 9295-9301
Published online Oct 26, 2021. doi: 10.12998/wjcc.v9.i30.9295
Table 1 Characteristics of fenofibrate-induced liver injury based on prior case reports
Ref.Demographic and clinical characteristics
Course of illness

Initial values
Location
Sex
Age, yr
Daily dose (mg)
Symptoms
Latency
Outcome
ALT(U/L)
ALP(U/L)
Total Bilirubin (mg/dL)
INR
Present caseSouth KoreaM65135 mgJaundice, pruritis 6 wkRecovery, 3 wk172118215.990.92
Ma et al[13], 2019ChinaM65200 mgEpigastric discomfort, nausea,fatigue2 dRecovery, 2 wk 1136.7279.71.91NA
Dohmen et al[7], 2005JapanF66150 mgFever, anorexia, hypochondrial discomfort11 dRecovery, 2 wk2165371.8NA
Rigal et al[14], 1989FranceF74200 mgJaundice2 yrRecovery, 2 mo14303154.6NA
Ho et al[8], 2004TaiwanM61300 mgJaundice, dark urine, fatigue2 wkRecovery, 2 mo2492599.3NA
Case 1 (Ahmad et al[6], 2017)CaucasianM43145 mgJaundice, dark urine, pale stool, pruritis6 wkRecovery53344020.61.04
Case 2 (poor prognosis) (Ahmad et al[6], 2017)CaucasianM6148 mgJaundice, rash, pruritis8 wkDeath (renal failure) at 26 mo835184.71.40
Case 3 (Ahmad et al[6], 2017)HispanicF37160 mgJaundice, nausea, fatigue, myalgia, abdo pain5 wkRecovery3323448.40.80
Case 4 (Ahmad et al[6], 2017)CaucasianM43145 mgJaundice, nausea, fatigue, dark urine, pale stool, fever, pruritis7 wkUnknown1002185.91.00
Case 5 (poor prognosis) (Ahmad et al[6], 2017) Jaward et al. 2017[6]CaucasianM41160 mgJaundice, abdominal pain, nausea 40 wkLiver Transplant, at 8 mo781958.04.3
Case 6 (Ahmad et al[6], 2017)HispanicM54134 mgFatigue56 wkRecovery5841060.5NA
Case 7 (Ahmad et al[6], 2017)CaucasianF4448 mgJaundice, dark urine, fatigue18 wkRecovery1197795.11.00