Autism with dysphasia accompanied by mental retardation caused by FOXP1 exon deletion: A case report

Table 1 Summarize the medical records reported in the past

Time of Publication	Age of the patient	Mutations in the positioning	Nucleic acid change	Amino acid change	Form of mutation	Language barrier	Motor retardation	Time to sit alone	Time to walk alone	Change in perception	Time to speak word	Face change	Stereotyped behavior
2009	23 mo	Chr3:71164161-71958845				+	+	15 mo	18 mo	+	23 mo	+	NA
2010	3 yr and 10 mo	Chr3:70549923-71618670			Missing	+	+	NA	16 mo	NA	41 mo	+	NA
2010	7 yr	Chr3:70807767-71305965			Missing	+	+	NA	24 mo	+	42 mo	NA	NA
	5 yr and 6 mo	Chr3:71021785	c.1573C>T	p.R525	Variation	+	+	12 mo	36 mo	+	42 mo	+	NA
	6 yr	Chr3:tel:70341246-70341247 and cen:71388173-71388174			Missing	+	+	8 mo	24 mo	+	42 mo	+	NA
2010	15 yr and 11 mo	Chr3:71114875-71504640/exons4-14			Missing	+	+	NA	18-20 mo	+	3 yr	NA	+
	9 yr and 11 mo	3p14.1	c.1573C>T	p.R525X	Variation	+	+	NA	18-20 mo	+	6 yr	NA	+
2011	NA	Chr3:71132860	+T	p.Ala339SerfsX4	Insert	+	+	NA	NA	+	NA	NA	+
2012	NA	Chr3:62133183-71072125			Missing	+	+	NA	NA	+	NA	NA	NA
2013	7 yr	Chr3:71041636-71229421			Missing	+	+	1 yr	25 mo	+	52 mo	+	NA
2015	14 yr	Chr3:71027059-71027060	c.1267-1268		Missing	+	+	+	13 mo	+	20 mo	+	+
2014	2 yr	Chr3:71021758	c.1600T>C	p.W534R	Variation	NA	NA	NA	NA	NA	NA	+	NA
2016	11 yr	Chr3:71026829	c.1393A>G	p.R465G	Variation	+	+	NA	21 mo	+	NA	+	+
	7 yr	Chr3:71021818	c.1540C>T	p.R514C	Variation	+	+	NA	17 mo	+	NA	+	+
	15 yr	Chr3:71027010	c.1317C>G	p.Y439	Variation	+	+	NA	21 mo	+	NA	+	+
This case	5 yr	3p14.1,exons6-21			Missing	+	+	9 mo	2 yr	+	NA	+	+

+: Positive result; -: Negative; NA: Not detected.