Efficacy of different antibiotics in treatment of children with respiratory mycoplasma infection

Table 1 Baseline data comparison between the clarithromycin group and the erythromycin group, n (%)

Baseline data	Clarithromycin group (n = 53)	Erythromycin group (n = 53)	χ2/t	P value
Gender			0.641	0.423
Male	28 (52.83)	29 (54.72)
Female	25 (47.17)	24 (45.28)
School
Kindergarten	11 (20.75)	10 (18.87)	0.111	0.739
Primary school	38 (71.70)	37 (69.81)	0.086	0.769
Junior high school	4 (7.55)	6 (11.32)	0.832	0.362
Age	6.74 (1.25)	6.83 (1.22)	1.050	0.862

Table 2 Comparison of the total clinical effectiveness in the clarithromycin group and the erythromycin group, n (%)

Group	Number of cases	Invalid	Effective	Marked effect	Total clinical effectiveness
Clarithromycin group	53	2 (3.77)	19 (35.85)	32 (60.38)	51 (96.23)
Erythromycin group	53	13 (24.53)	22 (41.51)	18 (33.96)	40 (75.47)
χ2	-	17.739	0.675	14.005	17.739
P value	-	0.001	0.411	0.001	0.001

Table 3 Hospital stay time, drug cost, and antipyretic time of the clarithromycin group vs the erythromycin group (mean ± SD)

	Clarithromycin group (n = 53)	Erythromycin group (n = 53)	t	P value
Hospital stays (d)	15.14 ± 2.01)	20.63 ± 3.15	10.696	0.001
Drug cost (Yuan)	1654.63 ± 100.21	2152.14 ± 163.48	18.889	0.001
Antipyretic time (d)	2.63 ± 0.57	4.06 ± 0.75	11.051	0.001

Table 4 Toxic side effects of the clarithromycin group compared with the erythromycin group, n (%)

Group	Number of cases	Stomach ache	Diarrhea	Nausea	Other	Incidence of side effects
Clarithromycin group	53	2 (3.77)	1 (1.89)	2 (3.77)	3 (5.66)	8 (15.09)
Erythromycin group	53	8 (15.09)	7 (13.21)	10 (18.87)	11 (20.75)	36 (67.92)
χ2	-	7.502	9.179	11.357	9.934	57.479
P value	-	0.006	0.002	0.001	0.002	0.001

Table 5 Comparison of medication compliance between the clarithromycin group and the erythromycin group, n (%)

Group	Number of cases	Full compliance	Obey	Disobey	Medication compliance
Clarithromycin group	53	40 (81.13)	12 (22.64)	1 (1.89)	52 (98.11)
Erythromycin group	53	18 (33.96)	20 (37.74)	15 (28.30)	38 (71.70)
χ2	-	45.537	5.409	27.211	27.211
P value	-	0.001	0.020	0.001	0.001