Observational Study
Copyright ©The Author(s) 2021.
World J Clin Cases. Aug 6, 2021; 9(22): 6329-6342
Published online Aug 6, 2021. doi: 10.12998/wjcc.v9.i22.6329
Table 1 Demographic characteristics of the high-functioning autism and control groups (personal information)
Items
Autism group, n = 110
Control group, n = 110
Z/χ2
P value
Age, median (min, max)14.5 (12.0, 19.1)14.4 (12.1, 19.0)-0.2680.789
Gender, n (%)00.999
Female17 (15.5)17 (15.5)
Male93 (84.5)93 (84.5)
Race, n (%)0.4740.491
Han nationality101 (91.8)98 (91.8)
Ethnic minority9 (8.2)12 (8.2)
Residence, n (%)0.3720.830
City94 (85.5)97 (88.2)
Town12 (10.9)10 (9.1)
Village4 (3.6)3 (2.7)
Table 2 Demographic characteristics of the high-functioning autism and control groups (family information)
Items
Autism group, n = 110
Control group, n = 110
Z/χ2
P value
Paternal education, n (%)19.450.001
Primary school1 (0.9)2 (1.8)
Middle school3 (2.7)18 (16.4)
High school22 (20.0)31 (28.2)
Undergraduate60 (54.5)49 (44.5)
Postgraduate24 (21.9)10 (9.1)
Maternal education, n (%)19.380.003
Primary school1 (0.9)4 (3.6)
Middle school5 (4.5)17 (15.5)
High school 20 (18.2)29 (26.4)
Undergraduate64 (58.2)52 (47.3)
Postgraduate20 (18.2)8 (7.3)
Family relationship, n (%)0.9420.624
Harmonious73 (66.4)78 (70.9)
Fine29 (26.4)23 (20.9)
Disharmony5 (4.5)6 (5.5)
Parents divorced3 (2.7)3 (2.7)
Family financial situation, n (%) (annual income CNY)15.840.003
< 3000015 (13.6)6 (5.5)
30000-5000028 (25.5)13 (11.8)
50000-7000019(17.3)24 (21.8)
70000-10000027 (24.5)27 (24.5)
> 10000021 (19.1)40 (36.4)
Family history of mental illness13.21< 0.001
Positive 151
Negative95109
Table 3 Comparison of Adolescent Health-related Risky Behavior Inventory total score and subscale scores between the two groups
Total scale/subscales
Autism group, n = 110
Control group, n = 110
Z
P value
Total score55.0 (38, 177)49.5 (38, 88)-3.3140. 001
Aggression and violence15.0 (10, 50)13.0 (10, 29)-3.0450.002
Health compromising behavior10.0 (5, 19)8.0 (5, 17)-2.2130.027
Rule breaking10.0 (7, 35)9.5 (7, 18)-0.7410. 458
Unprotected sex5.0 (5, 25)5.0 (5, 7)-4.197< 0. 001
Suicide and self-injury6.0 (5, 25)5.0 (5, 17)-2.5810.010
Substance use6.0 (6, 25)6.0 (6, 9)-0.7660. 444
Table 4 Correlation coefficients between the Adolescents Health-related Risky Behavior Inventory scores and the results of demographic characteristics, Autism Spectrum Screening Questionnaire and Inventory of Subjective Life Quality for Child and Adolescent
Total scale/subscale
AV
HCB
US
SS
Total score of AHRBI
Residence0.23610.3002-0.1320.1510.2512
Father’s education background0.031-0.34420.2171-0.173-0.091
Mother’s education background-0.115-0.23910.143-0.1951-0.162
Family financial situation-0.0310.0010.024-0.0080.003
Family relationship0.19510.1360.0090.1730.2241
ASSQ
Restricted and repetitive behavior0.0790.1460.1440.0100.136
Social interactiondisorder0.0150.2010.019-0.0050.093
Communicationbarriers0.0720.25210.128-0.0250.151
ISLQ
Cognitive subscale-0.2331-0.133-0.027-0.2381-0.2501
Family life-0.2331-0.036-0.013-0.145-0.181
Peer interaction-0.128-0.177-0.095-0.110-0.181
School life-0.2932-0.28810.066-0.2972-0.3352
Life environment-0.047-0.063-0.047-0.038-0.095
Self-cognition-0.1300.013-0.030-0.181-0.110
Emotional subscale-0.3812-0.059-0.131-0.3542-0.3542
Depression experience-0.3152-0.100-0.107-0.3302-0.3152
Anxiety experience-0.3272-0.039-0.112-0.2851-0.3012
Body emotion-0.34520.058-0.122-0.2221-0.2431
Table 5 Correlation coefficients between the Adolescents Health-related Risky Behavior Inventory scores and the results of intelligence quotient, Theory of Mind and expression recognition
Total scale/subscale
AV
HCB
US
SS
Total score of AHRBI
IQ
Verbal IQ0.042-0.138-0.164-0.050-0.008
Performance IQ0.012-0.181-0.2451-0.059-0.047
Full-scale IQ0.048-0.075-0.24720.0060.009
ToM test
First-order belief test0.087-0.1810.035-0.014-0.037
Second-order belief test-0.061-0.011-0.2741-0.050-0.043
Expression recognition
Easy facial recognition score-0.122-0.214-0.30620.022-0.124
Complex facial recognition score0.144-0.104-0.0310.0760.097
Total scores of expression recognition-0.017-0.2431-0.23310.075-0.043
Table 6 Multiple linear regression analysis of aggression and violence, health compromising behavior, unprotected sex, suicide and self-injury subscales and total score of Adolescents Health-related Risky Behavior Inventory
Model
Unstandardized coefficients
t
P value
95% Confidence interval for B
B
SE
Lower bound
Upper bound
AV
Emotional subscale-0.2680.068-3.954< 0.001-0.403-0.133
HCB
School life experience-0.1520.053-2.8410.006-0.258-0.045
US
Total IQ scores-0.0320.015-2.0660.042-0.062-0.001
Score of second-order belief test-1.3210.428-3.0880.003-2.173-0.470
SS
Depression experience-0.3210.073-4.371< 0.001-0.467-0.175
Total score of AHRBI
Depression experience-1.6030.444-3.6130.001-2.487-0.719