Primary liver actinomycosis in a pediatric patient: A case report and literature review

Table 1 Summary of data on reports of primary hepatic actinomycosis in English language

Ref.	Age (yr)	Sex	Manifestation	Involved segment	Diagnostic methods	Antibiotics and total duration
Yang et al[12]	55	M	UAP, LW	S2, S3 and S4	Left lobe resection/histology	PG, 4 wk
Eve[19]	60	M	UAP	UN	Autopsy/histology	UN
Zeng et al[11]	38	M	UAP, fever	Left lobe	Hepatectomy/histology	Cefoperazone, 7 d
Vargas et al[20]	64	M	UAP, anorexia, LW	S2, S3	Hepatectomy/histology	ACA, 6 mo
Miyamoto and Fang[23]	30	M	Fever, Chills, headache	Right lobe	Percutaneous drainage/pathogen	PG, Clindamycin, Doxycycline, 3 mo
Felekouras et al[2]	53	M	Fever, Chills	Right lobe	Right posterior segmentectomy/histology	Ciprofloxacin, 6 wk
Lange et al[5]	73	F	Fever, UAP, LW	S7, S8	Biopsy guided by US/histology	Amoxicillin, 9 mo
Kanellopoulou et al[16]	70	M	Fever, LW, anorexia	Multifocal	Biopsy guided by US/histology	AS + oral Amoxicillin, 2 wk
Yamada et al[13]	20	M	Fever, UAP	Right lobe	Hepatectomy/histology	Erythromycin, chlortetracycline, sulfonamide and streptomycin, duration not mentioned

ACA: Amoxycillin clavulanic acid; AS: Amoxicillin-sulbactam; F: Female; LW: Lose weight; M: Male; PG: Penicillin G; S2, S3, etc.: Liver segmented by Couinaud method; UAP: Upper abdominal pain; UN: Unmentioned; US: Ultrasound.

Table 2 Summary of data on reports of primary hepatic actinomycosis in English language

Ref.	Age (yr)	Sex	Manifestation	Involved segment	Diagnostic methods	Antibiotics and total duration
Culafić et al[4]	50	F	Fever, UAP, LW	Right lobe	Hepatectomy/histology	Benzylpenicillin + oral Amoxicillin, 7.5 mo
Sugano et al[18]	86	M	Fever, anorexia	Right lobe	Biopsy guided by US/histology + pathogen	Minocycline, Piperacillin, Ampicillin, 4 mo
Sharma et al[14]	34	M	Fever, UAP	Right lobe	Biopsy guided by CT/histology	Clindamycin, Ceftriaxone, 5 mo
Wayne et al[17]	65	M	Fever	S5, S6	Hepatectomy/histology	Doxycycline, 6 mo
Cetinkaya et al[3]	40	M	UAP, LW	Multifocal (right + left lobe)	Drainage/histology	PG, 3 mo
Kasano et al[6]	41	M	UAP	Right lobe	Surgery/histology	UN
Ha et al[15]	57	M	No symptom	Multifocal	Laparotomy biopsy/histology	PG, Ceftriaxone + oral Amoxicillin, 17 wk
Wong et al[21]	Case 1 46/Case 2 59	M/M	Fever/UAP	Multifocal/right lobe	Drainage/pathogen	PG, duration not mentioned
Kocabay et al[8]	40	F	Fever, LW, fatigue	S7, S8	Hepatectomy/histology	PG + oral Amoxicillin, 7.5 mo
Our case	9	F	Fever, LW, abdominal mass	Right lobe	Histology	Cefoperazone sodium and sulbactam sodium, 4 wk, + oral Amoxicillin, 1 yr

ACA: Amoxycillin clavulanic acid; AS: Amoxicillin-sulbactam; CT: Computed tomography; F: Female; LW: Lose weight; M: Male; PG: Penicillin G; S2, S3, etc.: Liver segmented by Couinaud method; UAP: Upper abdominal pain; UN: Unmentioned; US: Ultrasound.