Clinical and pathological features and risk factors for primary breast cancer patients

Table 1 Clinical and pathological features of patients with primary breast cancer

Clinical or pathological feature	n (%)
< 40 yr	34 (22.8)
40-59 yr	92 (61.8)
≥ 60 yr	23 (15.4)
Stage 0	16 (10.7)
Stage I	46 (30.9)
Stage II	57 (38.3)
Stage III	27 (18.1)
Stage IV	3 (2.0)
Luminal A	31 (20.8)
Luminal B (HER2 negative)	54 (36.2)
Luminal B (HER2 positive)	39 (26.2)
HER2 over expression type	11 (7.4)
Three negative type	14 (9.4)

HER2: Human epidermal growth factor receptor 2.

Table 2 Clinical and pathological features of patients with primary breast cancer in different age groups, n (%)

	< 40 yr	40-59 yr	≥ 60 yr	χ2	P value
Left	14 (41.2)	50 (54.3)	9 (39.1)	4.246	0.374
Right	20 (58.8)	40 (43.5)	13 (56.5)
Bilateral	0 (0.0)	2(2.2)	1 (4.3)
Carcinoma in situ	4 (11.8)	16 (17.4)	1 (4.3)	2.783	0.249
Invasive carcinoma	30 (88.2)	76 (82.6)	22 (95.7)
Tis	2 (5.9)	14 (15.2)	0 (0.0)	15.469	0.051
T1	16 (47.1)	31 (33.7)	10 (43.5)
T2	12 (35.3)	38 (41.3)	9 (39.1)
T3	4 (11.8)	7 (7.6)	1 (4.3)
T4	0 (0.0)	2 (2.2)	3 (13.0)
N0	17 (50.0)	57 (62.0)	10 (43.5)	6.486	0.371
N1	11 (32.4)	19 (20.7)	8 (34.8)
N2	5 (14.7)	8 (8.7)	2 (8.7)
N3	1 (2.9)	8 (8.7)	3 (13.0)
M0	34 (100)	9 1(98.9)	21 (91.3)	6.304	0.043
M1	0 (0.0)	1 (1.1)	2 (8.7)
Luminal A	7 (20.6)	16 (17.4)	8 (34.8)	6.154	0.63
Luminal B(HER2 negative)	13 (38.2)	32 (34.8)	9 (39.1)
Luminal B (HER2 positive)	8 (23.5)	28 (30.4)	3 (13.0)
HER2 over expression type	3 (8.8)	6 (6.5)	2 (8.7)
Three negative type	3 (8.8)	10 (10.9)	1 (4.3)

HER2: Human epidermal growth factor receptor 2.

Table 3 Correlation analysis of risk factors for patients with primary breast cancer

Variable	B	Standard error	Waldorf	P value	Exp (B)	95%CI of Exp (B)
						Lower limit	Upper limit
< 40 yr			14.059	0.001
40-59 yr	0.603	0.277	4.741	0.029	1.828	1.062	3.148
≥ 60 yr	2.059	0.568	13.128	< 0.001	7.842	2.574	23.892
Age at menarche (≤ 14 yr, > 14 yr)	0.965	0.261	13.633	< 0.001	2.626	1.573	4.384
Age at first birth	0.083	0.038	4.84	0.028	1.086	1.009	1.17
Number of births	0.266	0.176	2.291	0.13	1.305	0.924	1.843
Number of miscarriages	-0.207	0.112	3.414	0.065	0.813	0.652	1.013
Breastfeeding (mo)	-0.009	0.011	0.665	0.415	0.991	0.97	1.013
History of family malignant tumors	0.346	0.311	1.238	0.266	1.413	0.768	2.599
History of benign breast surgery	-1.355	0.489	7.664	0.006	0.258	0.099	0.673
Gynecological diseases	-0.357	0.299	1.42	0.233	0.7	0.389	1.258
Thyroid disease	-0.156	0.305	0.261	0.609	0.856	0.471	1.555