Typical ulcerative colitis treated by herbs-partitioned moxibustion: A case report

Table 1 Laboratory tests

Time	WBC (×109/L)	RBC (×1012/L)	HGB (g/L)	PLT (109/L)	HCT (L/L)	ESR (mm/h)	CRP (mg/L)
March 1, 2018	17.53	5.50	169	386	0.496	34	10.51
April 16, 2018	10.17	5.10	153	245	0.450	16	18.10
Visit1	12.42	5.35	164	300	0.466	10	3.77
Visit2	9.40	5.37	160	279	0.469	5	1.46
Visit3	10.77	5.32	160	262	0.460	/	2.84
Visit4	10.31	5.22	162	285	0.464	7	0.54
Visit5	9.91	5.38	165	294	0.484	10	2.80

Reference values: WBC: (3.97-9.15) × 10⁹/L; RBC: (4.09-5.74) × 10¹²/L; HGB: 131-172 g/L; PLT; (85-303)×10⁹/L; HCT: 0.380-0.508 L/L; ESR: 0.0-15.0 mm/h; CRP: 0-3 mg/L. WBC: White blood cell count; RBC: Red blood cell count; HGB: Hemoglobin; PLT: Platelets; HCT: Hematocrit; ESR: Erythrocyte sedimentation rate; CRP: C-reactive protein.

Table 2 Disease condition assessment

Time	Clinical symptoms(score)	IBDQ (score)	Mayo (score)	Baron (score)	VAS (score)	HADS-A (score)	HADS-D (score)
Visit1	21	110	6	2	21	21	15
Visit2	19	121	/	/	17	17	13
Visit3	15	150	/	/	14	10	8
Visit4	4	201	1	0	0	5	0
Visit5	3	203	/	/	0	5	0

Scores of clinical symptoms: Scores of clinical symptoms indicate the patient's current clinical symptoms, including the frequency, severity, and duration of abdominal pain; the frequency of diarrhea and stool characteristics; the amount of mucous in the stool and stool with pus and blood; the severity of abdominal distension and tenesmus; the percent reduction in food consumption; and symptoms of chills in the limbs and soreness in the waist and knees. The higher the score is, the more severe the disease. Inflammatory Bowel Disease Questionnaire scores: It reflects the quality of life for nearly two weeks in patients with inflammatory bowel disease including systemic symptoms, intestinal symptoms, social competence, and emotional competence. There are 32 questions, each with a different answer, 1 for the most severe and 7 for the least severe. The lower the total score is, the more severe the disease. Mayo scores: The Mayo scoring system is used to assess ulcerative colitis activity, a total score less than 2 points indicates symptom relief, 3-5 points indicates mild relief, 6-10 points indicates moderate activity, and 11-12 points indicates severe activity. Baron endoscopy scores: Endoscopic mucosal healing has become one of the therapeutic targets of ulcerative colitis, and in the Baron endoscopy score system: 0 points, vascular texture clearly visible, no spontaneous or contact bleeding; 1 point, mucosa has lesions but no bleeding; and 2 points, mucosa has severe contact bleeding, obvious ulcer formation, and spontaneous bleeding. The Visual Analog Scale abdominal pain scores: It reflects the patient's abdominal pain sensation over the previous 7 d. For each day, 0 represents no pain, and 10 represents severe pain; the total score over 7 d is calculated. Hospital Anxiety and Depression Scale, Hospital Anxiety and Depression Scale (HADS) (HADS-A, HADS-D): HADSincludes two subscales of HAS and HDS, with a total of 14 items, 7 of which rated anxiety and 7 of which rated depression. Each item was graded on a scale of 0-3, with higher scores indicating more severe symptoms of anxiety or depression. 0-7 points, asymptomatic; 8-10 points, suspicious; and 11-21 points, definitely present. The scores of anxiety and depression were divided into two subscales: 0-7 was negative; 8-10 is lightness; 11-14 is moderate; 15-21 is severe. Studies found that HADS has good reliability and validity, and 9 points can be used as the critical value of anxiety and depression to obtain better sensitivity and specificity. IBDQ: Inflammatory Bowel Disease Questionnaire; VAS: Visual Analog Scale; HADS: Hospital Anxiety and Depression Scale.