Relationship between granulomatous lobular mastitis and methylene tetrahydrofolate reductase gene polymorphism

Table 1 Differences in methylene tetrahydrofolate reductase C677T between the two groups

Groups	n	Genotype frequency			Allele frequency, %
		C/C	C/T	T/T	C	T
Experimental group	51	13	28	10	65.89	34.11
Control group	51	24	19	8	51.44	48.56
χ2		10.064	6.269	0.529	4.305	4.305
P value		0.002	0.012	0.467	0.038	0.038

Table 2 Differences in methylene tetrahydrofolate reductase A1298C between the two groups

Groups	n	Genotype frequency			Allele frequency, %
		A/A	A/C	C/C	A	C
Experimental group	51	37	13	1	85.30	14.70
Control group	51	35	14	2	82.35	17.65
χ2		0.422	0.099	0.673	0.321	0.321
P value		0.516	0.753	0.412	0.571	0.571