Two mechanically ventilated cases of COVID-19 successfully managed with a sequential ventilation weaning protocol: Two case reports

Table 1 Laboratory findings upon admission.

Blood analysis variable	Patient 1	Patient 2
WBC count, × 109/L	5.89	6.51
Neutrophil count, × 109/L	5.35	5.36
Lymphocyte count, × 109/L	0.42	0.93
Lactate, mmol/L	2.7	2.6
Creatinine, µmol/L	54.1	94.6
Urea, mmol/L	4.48	8.48
Albumin, g/L	34.6	35.5
Alanine aminotransferase, U/L	15.7	34.8
Total bilirubin, µmol/L	8.4	12.2
Nucleic acid result	+	+

WBC: White blood cells.

Table 2 PaO₂/FiO₂ ratios during mechanical ventilation

Time point	PaO2/FiO2 ratio (mmHg)
	Patient 1	Patient 2
Admission to ICU	136	68
After 2 h of NIV	141	116
Day 1 of MV	153	190
Day 2 of MV	227	176
Day 3 of MV	308	258
Day 4 of MV	318	269
Day 5 of MV	334	258
Day 6 of MV	340	316
Day 7 of MV	318	362
Day 8 of MV	+	+

Patient 1 and Patient 2 received MV for 8 d and 7 d, respectively. ICU: Intensive care unit; NIV: Noninvasive ventilation; MV: Mechanical ventilation.