Considerations for routine coagulation monitoring with rivaroxaban: A case report and review of the literature

Table 1 Serial coagulation studies

	PT (s)	aPTT (s)	INR
Reference range	11.0-15.0	28.0-42.5	0.84-1.27
Before treatment	15.6	39.2	1.25
Day 2 of drug administration	64.4	99.3	7.68
Day 1 after drug stopped	25.2	63.3	2.31
Day 2 after drug stopped	16.1	44.6	1.3
Day 3 after drug stopped	17.1	45.1	1.41
Day 4 after drug stopped	15.2	42.1	1.21
Day 5 after drug stopped: drug administration resumed
2 h after second drug administration	18.6	55.7	1.57
6 h after second drug administration	27.7	68.8	2.61

aPTT: Activated partial thromboplastin time; PT: Prothrombin time; INR: International normalized ratio.