Hydroxychloroquine-induced renal phospholipidosis resembling Fabry disease in undifferentiated connective tissue disease: A case report

doi:10.12998/wjcc.v7.i24.4377

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 7, Issue 24

This Article

Academic Content and Language Evaluation of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Supplementary Materials of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (6309)

All Articles published online

The chart showing PDF series, WORD series, HTML series, Figures (1-2) series, Tables (1-1) series.

Item

Count

PDF

382

WORD

176

HTML

4054

Figures (1-2)

209

Tables (1-1)

201

Sum=5022

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

523

Download

764

Sum=1287

Dec 26, 2019 (publication date) through May 6, 2024

Times Cited of This Article

Times Cited (14)

Journal Information of This Article

Publication Name

World Journal of Clinical Cases

ISSN

2307-8960

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Case Report

World J Clin Cases. Dec 26, 2019; 7(24): 4377-4383
Published online Dec 26, 2019. doi: 10.12998/wjcc.v7.i24.4377

Table 1 The timeline of treatment

Time	Symptoms	Diagnoses	Treatments
2008	Canker sores	Undifferentiated connective tissue disease	Low doses of prednisone: 5 mg
	White blood cell count: 1.8 × 10⁹/L
	ANA: 1:320(+)
	Blood complements: Normal
	Serum creatinine: 66 µmol/L
2016	Facial erythema	Undifferentiated connective tissue disease	Hydroxychloroquine; Prednisone
2016	Decreased blood complements	Undifferentiated connective tissue disease	Hydroxychloroquine; Prednisone
April 2018	Weight loss	Undifferentiated connective tissue disease; Hydroxychloroquine -induced renal phospholipidosis	Withdrawal of hydroxychloroquine; Prednisone
	Weakness
	White blood count: 2.7-4.7 × 10⁹/L
	Urine erythrocytes: 28/µL
	Serum creatinine: 58 µmol/L
	24-h urinary protein, quantitative: 1120 mg
	ANA: 1:80(+)
	Complement C3: 0.58 g/L
	Complement C4: 0.09 g/L
	Renal biopsy: Renal phospholipidosis
	Mutation of GLA gene: Negative

ANA: Antinuclear antibody.

Citation: Wu SZ, Liang X, Geng J, Zhang MB, Xie N, Su XY. Hydroxychloroquine-induced renal phospholipidosis resembling Fabry disease in undifferentiated connective tissue disease: A case report. World J Clin Cases 2019; 7(24): 4377-4383
URL: https://www.wjgnet.com/2307-8960/full/v7/i24/4377.htm
DOI: https://dx.doi.org/10.12998/wjcc.v7.i24.4377