Clinical significance and role of up-regulation of SERPINA3 expression in endometrial cancer

Table 1 Relationship between SERPINA3 expression and pathologic features of endometrial cancer

Variable		N	SERPINA3 protein		X2	P-value
			-	+
Pathological grade	I	45	19	26	9.774	< 0.05
	II	27	4	23
	III/IV	8	0	8
Clinical stage	G1	21	10	11	6.351	< 0.05
	G3	32	5	27
	G2/G3	27	8	19
Menopause	Yes	41	20	21	0.864	> 0.05
	No	39	15	24
Vascular invasion	≤ 50%	52	7	45	16.953	< 0.05
	> 50%	28	16	12
Lymph node metastasis	Positive	24	1	23	10.115	< 0.05
	Negative	56	22	34

“-” indicates the negative expression of SERPINA3; “+” indicates the positive expression of SERPINA3.

Table 2 Factors influencing the prognosis of patients with endometrial cancer

Factor	B	SE	df	P	95%CI for Exp (B)
Pathological grade	0.6567	0.0149	1	0.000	0.5385-0.8865
Clinical stage	0.7337	0.0140	1	0.000	0.5689-0.8561
Vascular invasion	0.7685	0.0208	1	0.000	0.4414-0.9836
Lymph node metastasis	0.6605	0.0145	1	0.000	0.5176-0.9074

B: Regression coefficient; CI: Confidence index; Exp (B): Odds ratio.