Changes in corneal endothelial cell density in patients with primary open-angle glaucoma

Table 1 Endothelial cell characteristics of study groups

	POAG, n = 60	Control, n = 60	P value
CD, cells/mm²	2757 ± 262	2959 ± 236	< 0.001
SD, μm²	153.87 ± 29.13	140.65 ± 19.53	0.008
CV, %	43.48 ± 7.71	43.06 ± 5.65	0.749
6A, %	49.45 ± 8.23	49.08 ± 9.11	0.831
AVE, μm²	364.37 ± 34.05	322.23 ± 54.69	< 0.001
MAX, μm²	963.52 ± 214.04	827.57 ± 198.18	0.002
MIN, μm²	78.10 ± 16.59	69.37 ± 17.33	0.013

POAG: primary open-angle glaucoma; CD: Cell density; SD: Standard deviation; CV: Coefficient of variation; 6A: Percentage of hexagonal cells; AVE: Average cell area; MAX: Maximum cell area; MIN: Minimum cell area.

Table 2 Endothelial cell characteristics of glaucoma subgroups

	With medication, n = 35	Untreated, n = 25	P value
CD, cells/mm²	2686 ± 233	2856 ± 272	0.043
6A, %	49.80 ± 8.32	48.96 ± 8.25	0.929
AVE, μm²	364.31 ± 34.41	364.44 ± 34.24	0.998
MAX, μm²	963.70 ± 187.97	963.26 ± 250.14	0.922
MIN, μm²	80.47 ± 16.28	74.78 ± 16.77	0.089

CD: Cell density; 6A: Percentage of hexagonal cells; AVE: Average cell area; MAX: Maximum cell area; MIN: Minimum cell area.