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©The Author(s) 2019.
World J Clin Cases. Jun 6, 2019; 7(11): 1291-1301
Published online Jun 6, 2019. doi: 10.12998/wjcc.v7.i11.1291
Published online Jun 6, 2019. doi: 10.12998/wjcc.v7.i11.1291
Table 1 Baseline characteristics of patients in PiCCO and control groups
PiCCO group, n = 30 | Control group, n = 30 | P value | |
Age in yr | 76.37 ± 6.67 | 75.93 ± 6.55 | 0.801 |
Male | 18 (60.0%) | 16 (53.3%) | 0.602 |
BMI | 24.89 ± 2.90 | 24.50 ± 3.52 | 0.752 |
Comorbidities | |||
Hypertension | 18 (60.0%) | 15 (50.0%) | 0.436 |
Hyperlipidemia | 8 (26.7%) | 7 (23.3%) | 0.766 |
Diabetes | 8 (26.7%) | 7 (23.3%) | 0.766 |
Pneumonia | 8 (26.7%) | 6 (20.0%) | 0.542 |
Respiratory failure | 3 (10.0%) | 4 (13.3%) | 0.688 |
APACHE II score | 24.07 ± 6.54 | 26.03 ± 7.00 | 0.266 |
SOFA score | 10.07 ± 3.34 | 10.09 ± 3.23 | 0.330 |
Hs-TnI in ng/mL | 0.39 ± 0.32 | 0.48 ± 0.32 | 0.304 |
NT-proBNP in pg/mL | 10459.47 ± 4784.84 | 12871.13 ± 8681.39 | 0.189 |
PaO2/FiO2 in mmHg | 239.18 ± 96.67 | 252.50 ± 109.64 | 0.619 |
Lac in mmol/L | 2.32 ± 1.13 | 2.40 ± 1.35 | 0.820 |
Table 2 Comparison of APACHE II score, SOFA score, Hs-TnI, NT-proBNP, PaO2/FiO2 and Lac on day 1, 3 and 7 after treatment between PiCCO and control groups
Group | No. | Treatment time | APACHE II score | SOFA score | Hs-TnI (ng/mL) | NT-proBNP (pg/ml) | PaO2/FiO2 (mmHg) | Lac (mmol/L) |
Control group | 30 | 1 d | 25.03 ± 7.35 | 11.31 ± 3.57 | 0.54 ± 0.33 | 13781.31 ± 9508.70 | 260.32 ± 111.50 | 2.41 ± 1.17 |
3 d | 22.00 ± 5.61 | 9.00 ± 3.39 | 0.40 ± 0.35 | 11537.69 ± 9701.62 | 294.94 ± 102.80 | 2.30 ± 1.03 | ||
7 d | 17.57 ± 4.89 | 7.09 ± 3.34 | 0.33 ± 0.28 | 9083.04 ± 7702.01 | 341.10 ± 98.05 | 1.99 ± 0.70 | ||
PiCCO Group | 30 | 1 d | 21.10 ± 5.95a | 8.37 ± 3.44b | 0.34 ± 0.25a | 8947.00 ± 5739.86a | 284.05 ± 127.06 | 2.15 ± 1.13 |
3 d | 17.52 ± 4.88b | 6.38 ± 3.05b | 0.17 ± 0.24b | 7294.83 ± 3638.23a | 346.96 ± 108.39 | 1.80 ± 0.95 | ||
7 d | 11.89 ± 3.38b | 4.07 ± 2.02b | 0.11 ± 0.14b | 5939.14 ± 2396.84a | 395.36 ± 88.20a | 1.52 ± 0.74a |
Table 3 Infusion and urine volume in patients in PiCCO and control groups
Group | No. | Time frame | Infusion volume in mL | Urine volume in mL |
Control group | 30 | 0-1 d | 2673.52 ± 945.22 | 1895.28 ± 717.58 |
1-2 d | 2806.61 ± 724.07 | 2111.75 ± 684.02 | ||
2-3 d | 2643.42 ± 674.59 | 2199.85 ± 666.83 | ||
PiCCO group | 30 | 0-24 h | 3201.07 ± 967.64a | 2492.67 ± 868.05b |
24-48 h | 3162.48 ± 770.95 | 2363.10 ± 755.36 | ||
48-72 h | 2842.76 ± 765.30 | 2502.76 ± 728.34 |
Table 4 Comparison of primary and secondary outcomes between PiCCO and control groups
PiCCO group, n = 30 | Control group, n = 30 | P value | |
Primary outcome | |||
ADL score | 66.83 ± 14.65 | 11.33 ± 5.71 | 0.000 |
Secondary outcomes | |||
Days on vasoactive agents | 10.04 ± 2.52 | 12.09 ± 3.16 | 0.013 |
Duration of mechanical ventilation in d | 8.13 ± 1.51 | 10.81 ± 2.10 | 0.000 |
Days on MV | 9.21 ± 4.40 | 12.39 ± 4.14 | 0.011 |
EICU/CCU length of stay | 12.57 ± 2.78 | 14.83 ± 2.59 | 0.005 |
Pulmonary edema | 18 (60%) | 21 (70%) | 0.589 |
Table 5 The monitoring indexes of PiCCO group at three point-in-times
Index | 24 h | 48 h | 72 h | Integral analysis | Multiple comparison | ||||
Adjustment coefficients | F | P | P1 | P2 | P3 | ||||
CI in L/min/m2 | 2.16 ± 0.43 | 2.62 ± 0.39 | 2.88 ± 0.91 | 0.835 | 13.723 | 0.001 | 0.000 | 0.000 | 0.104 |
EVLWI in mL/kg | 8.95 ± 1.85 | 7.59 ± 1.45 | 6.84 ± 0.82 | 1.024 | 21.669 | 0.000 | 0.001 | 0.000 | 0.018 |
ITBVI in mL/m2 | 972.49 ± 104.28 | 753.91 ± 85.28 | 583.18 ± 65.61 | 0.799 | 199.825 | 0.000 | 0.000 | 0.000 | 0.000 |
GEDVI in mL/m2 | 783.85 ± 88.36 | 604.28 ± 94.11 | 452.29 ± 67.89 | 0.948 | 133.476 | 0.000 | 0.000 | 0.000 | 0.000 |
- Citation: Zhang YB, Zhang ZZ, Li JX, Wang YH, Zhang WL, Tian XL, Han YF, Yang M, Liu Y. Application of pulse index continuous cardiac output system in elderly patients with acute myocardial infarction complicated by cardiogenic shock: A prospective randomized study. World J Clin Cases 2019; 7(11): 1291-1301
- URL: https://www.wjgnet.com/2307-8960/full/v7/i11/1291.htm
- DOI: https://dx.doi.org/10.12998/wjcc.v7.i11.1291