Acetaminophen-induced acute pancreatitis: A case report and literature review

Table 1 Summary of 11 cases of acetaminophen-induced acute pancreatitis

Year	Age/gender	APAP (g)	Serum APAP	AMS (IU/L)	ALT (IU/L)	TBil	NAC	Ref.
1977	31/F	60	NA	1440	300	H	No	[7]
1977	41/F	25	NA	1250	NA	H	No	[8]
1986	19/M	25	62 μg/mL	1500	380	NA	Yes	[9]
1991	34/F	9.37-13	77.7 μg/mL	936	225	NA	Yes	[10]
1995	48/F	25	NA	300	8700	NA	No	[11]
1997	74/F	NAa	31 μg/mL	787	3070	H	Yes	[12]
2001	47/M	4	NA	498	408	H	No	[13]
2009	35/F	3.97-5.3b	NA	1414	75 (H)	Normal	No	[14]
2009	17/F	15	Below	529	Normal	Normal	No	[15]
2012	40/F	H	NA	NAc	Normal	Normal	Yes	[16]
2014	19/F	78-120	208.4 μg/mL	638	9689	H	NA	[17]

^aA detailed medical history was difficult to obtain from this patient due to her confused mental state;

^b3.97-5.3 g/d for 1 mo;

^cAbdominal CT showed features suggestive of acute pancreatitis, AMS was not available. APAP: Acetaminophen; AMS: Serum amylase; ALT: Alanine aminotransferase; TBil: Total bilirubin; NA: Not available; NAC: N-acetylcysteine; H: High.

Table 2 Causes of acute pancreatitis

	Causes of acute pancreatitis
Common causes	Gallstones, alcohol misuse, hyperlipidemia
Other causes	Hypercalcemia, autoimmune, idiopathic, drugs, trauma, tumor