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World J Clin Cases. Dec 16, 2014; 2(12): 873-882
Published online Dec 16, 2014. doi: 10.12998/wjcc.v2.i12.873
Published online Dec 16, 2014. doi: 10.12998/wjcc.v2.i12.873
Table 1 Demographic and clinical characteristics of eosinophilic chronic rhinosinusitis with nasal polyps and non-eosinophilic chronic rhinosinusitis with nasal polyps
ECRSwNP | NECRSwNP | |
n (%) | 27 (45%) | 33 (55%) |
Age (yr), mean ± SD | 46.93 ± 12.35 | 40.27 ± 13.47 |
M/F | 20/7 | 24/9 |
With AR (%) | 74.10% | 48.5% |
With asthma (%) | 18.50% | 12.1% |
Duration of symptom (yr) | 5.50 ± 3.92 | 8.55 ± 6.93 |
VAS | 4.04 ± 1.01 | 3.99 ± 1.09 |
Score of olfactory dysfunction | 5.59 ± 2.54 | 5.21 ± 2.66 |
Score of polyps | 3.59 ± 1.11b | 2.06 ± 0.82 |
Incidence of bilateral polyps | 92.6%b | 39.9% |
Score of disease on CT | 14.42 ± 3.84b | 9.64 ± 3.37 |
Serum IgE (kU/L) | 236.72 ± 157.77 | 167.97 ± 176.77 |
Blood eosinophil count (× 109/L) | 0.44 ± 0.24b | 0.21 ± 0.11 |
Blood eosinophil percentage (%) | 6.49 ± 3.27b | 3.42 ± 1.87 |
Tissue eosinophil count/HPF | 31.56 ± 21.37b | 0.91 ± 0.80 |
Table 2 Computed tomography features of eosinophilic chronic rhinosinusitis with nasal polyps and non-eosinophilic chronic rhinosinusitis with nasal polyps
ECRSwNP(n = 27) | NECRSwNP(n = 33) | |
Total disease score of sinuses | 14.42 ± 3.84b | 9.64 ± 3.37 |
Number of involved sinuses | 7.88 ± 1.22b | 5.64 ± 1.49 |
Percentage of involvement in all sinuses | 23.1%a | 3.0% |
Incidence of bilateral diseases in individual sinuses | ||
Frontal | 53.8%b | 12.1% |
Sphenoid | 38.5%a | 9.1% |
Anterior ethmoid | 53.8%a | 12.1% |
Posterior ethmoid | 100.0%b | 75.8% |
Maxillary | 96.2%a | 69.7% |
OMC | 69.2%a | 36.4% |
Score of diseases in individual sinuses | ||
Frontal | 1.81 ± 1.51a | 0.88 ± 0.91 |
Sphenoid | 1.23 ± 1.28a | 0.55 ± 0.76 |
Anterior ethmoid | 3.27 ± 0.90b | 2.27 ± 0.87 |
Posterior ethmoid | 3.04 ± 1.04b | 1.52 ± 0.95 |
Maxillary | 2.23 ± 0.43 | 2.15 ± 0.69 |
OMC | 2.85 ± 1.60 | 2.27 ± 1.20 |
Table 3 Diagnostic sensitivity and specificity of blood eosinophil count or percentage for eosinophilic chronic rhinosinusitis
Ref. | Blood eosinophil count | Blood eosinophil percentage | ||||||
AUC | Cutoff value | Sensitivity | Specificity | AUC | Cutoff value | Sensitivity | Specificity | |
Zuo et al[52] | 0.873 | 0.16 × 109/L | 84.9% | 84.4% | 0.863 | 2.05% | 89.0% | 84.4% |
Wang et al[9] | - | - | - | - | 0.818 | 5.65% | 79.0% | 78.2% |
Hu et al[11] | 0.871 | 0.22 × 109/L | 74.2% | 86.5% | 0.864 | 3.05% | 80.3% | 75.3% |
Sakuma et al[13] | - | - | - | - | 0.880 | 6.00% | 97.4% | 70.7% |
- Citation: Wang ET, Zheng Y, Liu PF, Guo LJ. Eosinophilic chronic rhinosinusitis in East Asians. World J Clin Cases 2014; 2(12): 873-882
- URL: https://www.wjgnet.com/2307-8960/full/v2/i12/873.htm
- DOI: https://dx.doi.org/10.12998/wjcc.v2.i12.873