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World J Clin Cases. Dec 16, 2014; 2(12): 873-882
Published online Dec 16, 2014. doi: 10.12998/wjcc.v2.i12.873
Eosinophilic chronic rhinosinusitis in East Asians
En-Tong Wang, Yan Zheng, Peng-Fei Liu, Li-Juan Guo
En-Tong Wang, Yan Zheng, Peng-Fei Liu, Li-Juan Guo, Department of Otolaryngology, Head and Neck Surgery, Air Force General Hospital, Beijing 100142, China
Author contributions: Wang ET contributed to the study design and wrote the review; Zheng Y, Liu PF and Guo LJ were involved in the acquisition, analysis and interpretation of data.
Correspondence to: En-Tong Wang, MD, PhD, Department of Otolaryngology, Head and Neck Surgery, Air Force General Hospital, 30 Fucheng Road, Beijing 100142, China. wang_entong@sina.com
Telephone: +86-10-88420757 Fax: +86-10-88420757
Received: June 25, 2014
Revised: August 28, 2014
Accepted: September 16, 2014
Published online: December 16, 2014
Core Tip

Core tip: Chronic rhinosinusitis (CRS) is a common disease and currently classified into two types based on presence or absence of nasal polyps. CRS may also be subtyped into eosinophilic CRS (ECRS) and non-ECRS according to the presence of predominant tissue eosinophilic infiltration or not. ECRS differs significantly from non-ECRS in clinical characteristics, treatment outcomes and strategies, and underlying pathogenic mechanisms. ECRS is considered a special and recalcitrant subtype of CRS. The identification of ECRS is helpful to develop treatment strategies for this CRS subtype. Herein we review the clinical features, diagnosis, treatment and prognosis of ECRS in East Asians.