Saccharomyces boulardii as a single trigger of food protein-induced enterocolitis syndrome: Seven case reports

Table 1 Cases of Saccharomyces boulardii as a single trigger of food protein-induced enterocolitis syndrome

	Case No.	Age/sex	Feeding at diagnosis	Previous FPIES-like episode including this diagnosis	Vomiting beginning time after S. boulardii ingestion (hour)	Lethargy/pallor	Skin/respiratory symptom	Diarrhea	Increase of absolute neutrophil count above baseline count (cells/mL)
‘Confirmed’ isolated S. boulardii-FPIES	1	4 months/F	Breast	5	2	+/+	-/-	-	13346
	2	10 months/M	Breast/CM	2	3	+/+	-/-	+	6575
	3	6 months/M	Breast	1	1.5	+/+	-/-	+	3162
‘Possible’ isolated S. boulardii-FPIES	4	9 months/M	Breast/CM	2	1.5	+/+	-/-	+	Nd
	5	4 months/F	Breast	4	2	+/+	-/-	+	Nd
	6	7 months/F	Breast	2	1	+/+	-/-	+	Nd
	7	6 months/F	CM	3	1	+/+, cyanosis	-/-	+, bloody and purulent	Nd

CM: Cow’s milk; FPIES: Food protein-induced enterocolitis syndrome; F: Female; M: Male; Nd: Not done; S. boulardii, Saccharomyces boulardii.