Advantages of the single-center model in domino transplant processes: Operational planning and management experience

Table 1 Characteristics of donors and recipients

Characteristic	Donors (n = 169)	Recipients (n = 169)
Sex (M/F)	80/89 (47%/53%)	95/74 (56%/44%)
Mean age (years)	42.8 ± 8.5	43.2 ± 8.1

F: Female; M: Male.

Table 2 ABO blood type distribution among donors and recipients

Blood type	Donors	Recipients
A	55 (32.5)	61 (36.1)
B	32 (18.9)	34 (20.1)
AB	14 (8.3)	17 (10.0)
O	68 (40.2)	57 (33.7)
Total	169 (100)	169 (100)

Data are presented as n (%).

Table 3 Improvement in HLA mismatches

Characteristic	Intended pairs (mean ± SD)	Transplanted pairs (mean ± SD)	P value
Total HLA mismatches	4.7 ± 1.1	3.2 ± 0.8	< 0.001
DR mismatches	1.6 ± 0.5	0.9 ± 0.4	< 0.001

DR: Donor-recipient; SD: Standard deviation.

Table 4 Graft and patient survival rates

Characteristic	1-year survival (%)	3-year survival (%)	Median follow-up
Graft survival	96	92
Patient survival	98	94	36 months (range: 12-60 months)
Differences among chain types	-	-	No significant difference (P > 0.05)

Table 5 Immunological profiles, operating room parameters, and waiting times

Parameter	Value/range
PRA level (mean ± SD)	20% ± 8%
DSA threshold (MFI cutoff)	> 3000 MFI
ABO/HLA mismatch frequency	90%
Cold ischemia time, min	46 ± 9
Warm ischemia time, min	4 ± 1
Mean OR time per chain, h	4-6
Total surgeries per multichain session	4-6
Surgeries/day per surgeon	1-2
Median waiting time (months, IQR)	2.5 (1.0-6.0)

DSA: Donor-specific antibodies; IQR: Interquartile range; MFI: Mean fluorescence intensity; OR: Operating room; PRA: Panel reactive antibody.