Effect of early stepwise cardiopulmonary rehabilitation on function and quality of life in sepsis patients

Table 1 Comparison of general data of patients in the two groups

Items		Observation group, n = 40	Control group, n = 40	t/χ² value	P value
Age (yr)		52.28 ± 5.12	52.75 ± 6.21	0.392	0.695
Sex	Male	25 (62.50)	27 (67.50)	0.219	0.639
	Female	15 (37.50)	13 (32.50)
BMI (kg/m²)		22.79 ± 1.13	22.93 ± 1.22	0.532	0.595
Infection site	Abdominal cavity	7 (17.50)	8 (20.00)	0.569	0.752
	Blood system	5 (12.50)	7 (17.50)
	Lung	28 (70.00)	25 (62.50)
APACHEII		18.56 ± 3.94	18.21 ± 4.59	0.365	0.715

Data are n (%) or mean ± SD. APACHEII: Acute physiology and chronic health status score II; BMI: Body mass index.

Table 2 Comparison of changes in cardiac function before and after treatment

Groups	Time	CVP in cmH2O	cTnI in μg/L	BNP in pg/mL
Observation group, n = 40	Before treatment	3.36 ± 1.12	5.52 ± 1.03	825.34 ± 227.87
	After treatment	10.67 ± 2.28a	1.83 ± 0.48a	478.96 ± 153.54a
Control group, n = 40	Before treatment	3.54 ± 1.38	5.48 ± 0.86	846.59 ± 268.35
	After treatment	8.32 ± 2.08a	2.25 ± 0.96a	618.15 ± 166.82a
t value After treatment		4.815	2.474	3.882
P value After treatment		< 0.001	0.015	< 0.001

^aP < 0.05 compared with before treatment.

Data are mean ± SD. BNP: Brain natriuretic peptide; cTnI: Cardiac troponin I; CVP: Central venous pressure.

Table 3 Comparison of changes in lung function before and after treatment

Groups	Time	Diaphragmatic range of motion in mm	ScvO2	PaO2/FiO2 in mmHg
Observation group, n = 40	Before treatment	22.28 ± 4.63	0.55 ± 0.06	176.36 ± 25.87
	After treatment	46.94 ± 5.18a	0.73 ± 0.045a	312.44 ± 29.78a
Control group, n = 40	Before treatment	23.16 ± 5.12	0.54 ± 0.05	181.54 ± 26.45
	After treatment	43.72 ± 6.06a	0.69 ± 0.02a	285.61 ± 25.94a
t value after treatment		2.554	4.697	4.296
P value after treatment		0.012	< 0.001	< 0.001

^aP < 0.05 compared with before treatment.

Data are mean ± SD. PaO₂/FiO₂: Oxygenation index; ScvO₂: Central venous oxygen saturation.

Table 4 Comparison of changes in quality of life before and after treatment

Groups	Time	Role function	Somatic function	Emotion function	Cognitive function	Social function
Observation group, n = 40	Before treatment	68.79 ± 3.95	64.57 ± 3.62	65.77 ± 3.89	63.56 ± 3.85	64.93 ± 3.51
	After treatment	85.64 ± 3.98a	86.78 ± 3.16a	88.34 ± 4.09a	85.73 ± 3.59a	89.33 ± 2.27a
Control group, n = 40	Before treatment	68.47 ± 3.52	63.99 ± 3.06	65.82 ± 4.01	63.14 ± 4.12	65.02 ± 3.62
	After treatment	74.15 ± 3.23a	73.75 ± 3.49a	74.84 ± 3.97a	76.83 ± 4.25a	75.84 ± 3.24a
t value after treatment		14.177	17.503	14.979	10.117	21.566
P value after treatment		< 0.001	< 0.001	< 0.001	< 0.001	< 0.001

^aP < 0.05 compared with before treatment.

Data are mean ± SD.

Table 5 Comparison of complications

Groups	n	Ventilator-associated pneumonia	Tracheostomy	ICU-acquired frailty
Observation group	40	2 (5.00)	1 (2.50)	1 (2.50)
Control group	40	5 (12.50)	4 (10.00)	3 (7.50)
χ² value		0.626	0.853	0.263
P value		0.428	0.355	0.607

Data are n (%). ICU: Intensive care unit.