Retrospective Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Feb 6, 2024; 12(4): 729-736
Published online Feb 6, 2024. doi: 10.12998/wjcc.v12.i4.729
Effect of early stepwise cardiopulmonary rehabilitation on function and quality of life in sepsis patients
Ming-Hui Zheng, Wen-Jun Liu, Juan Yang
Ming-Hui Zheng, Division of Cardiovascular First Ward Departments of Internal Medicine, Liyuan Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430077, Hubei Province, China
Wen-Jun Liu, Department of Respiratory Medicine, PuRen Hospital Affiliated to Wuhan University of Science and Technology/Respiratory Medicine, Wuhan 430000, Hubei Province, China
Juan Yang, Department of Cardiology, Huanggang Central Hospital, Huanggang 438000, Hubei Province, China
Co-first authors: Ming-Hui Zheng and Wen-Jun Liu.
Author contributions: Zheng MH and Liu WJ designed the research; Yang J, Zheng MH, and Liu WJ contributed new reagents/analytical tools; Yang J, Zheng MH, and Liu WJ analyzed the data; Zheng MH and Liu WJ wrote the paper; All authors were involved in the critical review of the results and read and approved the final manuscript. Zheng MH and Liu WJ contributed equally to this work as co-first authors to this work. The reasons for designating Zheng MH and Liu WJ as co-first authors are threefold. First, the research was performed as a collaborative effort, and the designation of co-corresponding authorship accurately reflects the distribution of responsibilities and burdens associated with the time and effort required to complete the study and the resultant paper. This also ensures effective communication and management of post-submission matters, ultimately enhancing the paper’s quality and reliability. Second, the overall research team encompassed authors with a variety of expertise and skills from different fields, and the designation of co-first authors best reflects this diversity. This also promotes the most comprehensive and in-depth examination of the research topic, ultimately enriching readers’ understanding by offering various expert perspectives. Third, Zheng MH and Liu WJ contributed efforts of equal substance throughout the research process. The choice of these researchers as co-first authors acknowledges and respects this equal contribution, while recognizing the spirit of teamwork and collaboration of this study. In summary, we believe that designating Zheng MH and Liu WJ as co-first authors is fitting for our manuscript as it accurately reflects our team’s collaborative spirit, equal contributions, and diversity.
Institutional review board statement: This study protocol was approved by Huanggang Central hospital, and all the families have voluntarily participated in the study and have signed informed consent forms.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors declare having no conflicts of interest in relation to this paper.
Data sharing statement: Data generated from this investigation are available upon reasonable quest from the corresponding author.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Juan Yang, MM, Attending Doctor, Department of Cardiology, Huanggang Central Hospital, No. 126 Qi’an Road, Huangzhou District, Huanggang 438000, Hubei Province, China. yang223332023@163.com
Received: November 6, 2023
Peer-review started: November 6, 2023
First decision: November 16, 2023
Revised: December 4, 2023
Accepted: January 8, 2024
Article in press: January 8, 2024
Published online: February 6, 2024
Processing time: 79 Days and 23.2 Hours
Abstract
BACKGROUND

Sepsis, as a non-limiting host infection disease, can be accompanied by serious complications such as organ failure, which seriously threatens patient quality of life.

AIM

To investigate the effect of early stepwise cardiopulmonary rehabilitation on cardiopulmonary function and quality of life in patients evacuated from mechanical ventilation with sepsis.

METHODS

A total of 80 patients with sepsis who were hospitalized in our hospital from January 2021 to January 2022 were selected and divided into the observation group (n = 40) and the control group (n = 40) according to the random number table method. The observation group was treated with early stepwise cardiopulmonary rehabilitation, and the control group was treated with a conventional treatment regimen. Cardiac function indexes (central venous pressure, cardiac troponin I, B-type brain natriuretic peptide), lung function indicators (diaphragmatic mobility, changes in central venous oxygen saturation, oxygenation index), and quality of life (Quality of Life Evaluation Scale) were compared between the two groups after treatment.

RESULTS

After treatment, the central venous pressure, diaphragm mobility, central venous oxygen saturation, oxygenation index, and Quality of Life Evaluation Scale scores in the observation group were higher than those in the control group, and the differences were statistically significant (P < 0.05). The observation group was less than that of the control group for other parameters, and the differences were statistically significant (P < 0.05).

CONCLUSION

Early stepwise cardiopulmonary rehabilitation can effectively enhance cardiac and pulmonary function and improve the quality of life in patients evacuated from mechanical ventilation with sepsis.

Keywords: Stepwise cardiopulmonary rehabilitation; Sepsis; Evacuation of mechanical ventilation; Cardiopulmonary function; Quality of life

Core Tip: Sepsis is an uncontrolled body infection, which can be life-threatening in severe cases. Therefore, it is extremely important to explore the intensive care measures for sepsis patients. In this study, early step-by-step cardiopulmonary rehabilitation was selected, and it was found that this treatment method can effectively improve the cardiopulmonary function of patients, improve life treatment, and improve prognosis.