Comparison of ovarian preservation versus oophorectomy on fertility outcomes in patients with endometriosis post-laparoscopic surgery: A prospective study

Table 1 Baseline characteristics, n (%)

Characteristic	Ovarian preservation group (n = 204)	Oophorectomy group (n = 108)	P value
Age (years), mean ± SD	32.4 ± 4.8	34.1 ± 5.2	0.11
BMI (kg/m2), mean ± SD	24.6 ± 3.9	25.1 ± 4.2	0.28
Nulliparous	137 (67.2)	77 (71.3)	0.45
ASRM stage
I	22 (10.8)	9 (8.3)	0.51
II	38 (18.6)	17 (15.7)	0.54
III	81 (39.7)	46 (42.6)	0.63
IV	63 (30.9)	36 (33.3)	0.67

ASRM: American Society for Reproductive Medicine; BMI: Body mass index.

Table 2 Postoperative pain scores (visual analog scale)

Time point	Ovarian preservation group (n = 204)	Oophorectomy group (n = 108)	P value
3 months	2.8 ± 1.6	2.6 ± 1.8	0.31
6 months	2.1 ± 1.4	1.9 ± 1.6	0.27
12 months	1.5 ± 1.2	1.3 ± 1.1	0.19
24 months	1.1 ± 0.9	0.9 ± 0.8	0.07

Table 3 Surgical complications, n (%)

Complication	Ovarian preservation group (n = 204)	Oophorectomy group (n = 108)	P value
Any complication	25 (12.3)	16 (14.8)	0.51
Bleeding	8 (3.9)	6 (5.6)	0.51
Infection	6 (2.9)	3 (2.8)	0.93
Bladder/bowel injury	4 (2.0)	3 (2.8)	0.63
Others	7 (3.4)	4 (3.7)	0.9

Table 4 Spontaneous pregnancy rates by age subgroup

Age subgroup	Ovarian preservation group	Oophorectomy group	P value
≤ 35 years	50.8% (74/146)	31.6% (24/76)	0.002
35 years	26.7% (15/58)	22.2% (7/32)	0.61

Table 5 Spontaneous pregnancy rates by American Society for Reproductive Medicine stage

ASRM stage	Ovarian preservation group	Oophorectomy group	P value
I/II	38.3% (23/60)	34.6% (9/26)	0.73
III	46.9% (38/81)	30.2% (14/46)	0.017
IV	39.5% (28/63)	24.1% (8/36)	0.038

ASRM: American Society for Reproductive Medicine.

Table 6 Outcomes by surgical technique (ovarian preservation group)

Outcome	Cystectomy (n = 138)	Drainage (n = 66)	P value
Spontaneous pregnancy rate	44.9% (62/138)	40.9% (27/66)	0.58
Recurrence rate	20.3% (28/138)	25.8% (17/66)	0.37