Published online Jul 26, 2024. doi: 10.12998/wjcc.v12.i21.4652
Revised: May 23, 2024
Accepted: June 7, 2024
Published online: July 26, 2024
Processing time: 66 Days and 19.3 Hours
Endometriosis is a chronic inflammatory condition affecting a significant propor
To compare the reproductive outcomes and recurrence rates between ovarian preservation and oophorectomy in women undergoing laparoscopic surgery for endometriosis.
This study was conducted at a tertiary care hospital between January 2019 and December 2023. A total of 312 women aged 18 to 40 years, diagnosed with endo
The ovarian preservation group exhibited a significantly higher spontaneous pregnancy rate than that in the oophorectomy group (43.6% vs 28.7%, P = 0.006). Moreover, the median time to spontaneous pregnancy was shorter in the ovarian preservation group (8.2 months vs 11.4 months, P = 0.018). Nonetheless, endometriosis recurrence was more prevalent in the ovarian preservation group (22.1% vs 11.1%, P = 0.014). The postoperative pain scores demonstrated similar improvements in both groups, with no significant differences observed. Subgroup analyses indicated that the benefit of ovarian preservation on spontaneous pregnancy rates was more evident among younger women (≤ 35 years) and those with advanced-stage endometriosis.
Ovarian preservation is associated with a high spontaneous pregnancy rate and a short time to pregnancy. However, because of the increased risk of recurrence, the decision should be based on age, fertility aspirations, and disease severity.
Core Tip: Preserving ovaries during laparoscopic surgery for endometriosis enhances spontaneous pregnancy rates and reduces time to conception. However, increased risk of disease recurrence necessitates individualized decision-making based on patient age, fertility goals, and disease severity.