Efficacy of percutaneous mechanical thrombus removal in acute lower extremity deep venous thrombosis

Table 1 Comparison of general information of the two groups of patients, n (%)

Item	PMT group (n = 24)	CDT group (n = 32)	P value
Sex
Male	8 (33.33)	13 (40.63)	0.616
Female	16 (66.67)	19 (59.37)
Age (years)	63.19 ± 14.04	62.80 ± 12.98	0.931
Time of onset (days)	7.15 ± 3.28	7.11 ± 3.39	0.961
Lower extremity DVT type
Central type	6 (25.00)	8 (25.00)	0.936
Mixed type	18 (75.00)	24 (75.00)
Distribution of affected limb
Left lower extremity	19 (79.17)	28 (87.50)	0.604
Right lower extremity	5 (20.83)	4 (12.50)
Risk factors
No obvious cause	8 (33.33)	10 (31.25)	0.857
History of surgical operations within 3 months	8 (33.33)	12 (37.50)	0.623
Stay in bed or sit for a long time	5 (20.83)	5 (15.63)	0.779
Malignant tumor	2 (8.33)	3 (9.37)	0.851
Hyperhomocysteinemia	2 (8.33)	1 (3.12)	0.524
Deep vein valve dysfunction	0 (0)	2 (6.25)	0.101
After delivery	2 (8.33)	0 (0)	0.057
Stent implantation	12 (50.00)	16 (50.00)	0.949
Iliac vein stenosis	15 (62.50)	22 (68.75)	0.686

PMT: Percutaneous mechanical thrombectomy; CDT: Catheter-directed thrombolysis; DVT: Deep venous thrombosis.

Table 2 Thrombus clearance effects in two groups of patients, n (%)

Argument	PMT group (n = 24)	CDT group (n = 32)	P value
Grade I thrombus clearance	1 (4.16)	2 (6.25)	0.732
Grade II thrombus clearance	13 (54.17)	22 (68.75)	0.265
Level III thrombus clearance	10 (41.67)	8 (25.00)	0.186

PMT: Percutaneous mechanical thrombectomy; CDT: Catheter-directed thrombolysis.

Table 3 Comparison of the two patient groups' respective rates of complications, n (%)

Argument	PMT group (n = 24)		CDT group (n = 32)		P value
	1 day after surgery	3 days after surgery	1 day after surgery	1 day after surgery
Minor bleeding	1 (4.17)	2 (8.33)	4 (12.50)	10 (31.25)	0.011
Severe bleeding	0 (0)	0 (0)	0 (0)	0 (0)
Infect	0 (0)	0 (0)	0 (0)	1 (3.13)
Severe pulmonary embolism	0 (0)	0 (0)	0 (0)	0 (0)
Complication rate	1 (4.17)	2 (8.33)	4 (12.50)	11 (34.38)
P value	0.551		0.039

PMT: Percutaneous mechanical thrombectomy; CDT: Catheter-directed thrombolysis.

Table 4 Comparison of preoperative and postoperative test indexes in percutaneous mechanical thrombectomy group

Time	Argument	Hemoglobin (g/L)	Creatinine (μmmol/L)
Before operation	MV	137.32	57.45
	SD	15.94	13.69
1 day after surgery	MV	125.19a	57.52
	SD	14.11	13.66
7 days after surgery	MV	137.15c	57.43
	SD	14.72	13.65

^aP < 0.05, indicates 1 day postoperatively compared with preoperatively; ^cP < 0.05, indicates 7 days postoperatively compared with preoperatively; MV: Mean value; SD: Standard deviation.

Table 5 Comparison of urokinase dosage, thrombolysis time, and hospitalization time between the two groups of patients

Argument	PMT group (n = 24)		CDT group (n = 32)		P value
	mean	SD	mean	SD
Urokinase dosage/10000 U	18.24	7.33	345.15	45.54	0.000
Thrombolytic time/hour	0.34	0.17	154.48	62.37	0.000
Hospitalization time/day	6.54	2.48	8.14	3.56	0.000

PMT: Percutaneous mechanical thrombectomy; CDT: Catheter-directed thrombolysis.

Table 6 Comparison of six-minute walk test between the two groups of patients

Group	6MWT before treatment/m	6MWT after treatment/m	t	P value
CDT group (n = 32)	331.24 ± 20.45	514.80 ± 24.77	32.367	0.000
PMT group (n = 24)	321.56 ± 18.23	553.12 ± 18.43	43.761	0.000
t	1.866	6.638	-
P value	0.068	0.000

6MWT: Six-minute walk test; PMT: Percutaneous mechanical thrombectomy; CDT: Catheter-directed thrombolysis.