Retrospective Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jul 26, 2024; 12(21): 4590-4600
Published online Jul 26, 2024. doi: 10.12998/wjcc.v12.i21.4590
Efficacy of percutaneous mechanical thrombus removal in acute lower extremity deep venous thrombosis
Jun-Qiang Xue, Ping Yin, Jian-Ping He, Hui Wei, Cui-Jie Geng, Yu-Xian Luo
Jun-Qiang Xue, Jian-Ping He, Cui-Jie Geng, Yu-Xian Luo, Department of Vascular Surgery, Shijiazhuang People's Hospital, Shijiazhuang 050011, Hebei Province, China
Ping Yin, Department of Laboratory Medicine, Shijiazhuang Hospital of Traditional Chinese Medicine, Shijiazhuang 050011, Hebei Province, China
Hui Wei, Catheter Room, Shijiazhuang People's Hospital, Shijiazhuang 050011, Hebei Province, China
Co-first authors: Jun-Qiang Xue and Ping Yin
Author contributions: Xue JQ and Yin P designed and wrote the manuscript; He JP, Wei H and Geng CJ analysed the data and plotted the graphs; Luo YX supervised the process; All authors reviewed the manuscript.
Supported by the Health and Wellness Commission of Hebei Province, No. 20160344; and the Health Commission of Shijiazhuang City, Hebei Province, No. 221200763.
Institutional review board statement: This study was approved by the Medical Ethics Committee of Shijiazhuang People's Hospital.
Informed consent statement: The data used in this study did not involve any personal privacy information of the patients. All patient data were obtained, recorded, and managed solely for the purposes of this study without causing any harm to the patients. Therefore, the informed consent requirement was waived by the ethics committee of Shijiazhuang People's Hospital.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: All data should be obtained by contacting the corresponding author.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yu-Xian Luo, MD, Chief Physician, Department of Vascular Surgery, Shijiazhuang People's Hospital, No. 365 Jianhua South Street, Yuhua District, Shijiazhuang 050011, Hebei Province, China. lyxxueguanwaike@163.com
Received: April 24, 2024
Revised: May 30, 2024
Accepted: June 13, 2024
Published online: July 26, 2024
Processing time: 66 Days and 19 Hours
Core Tip

Core Tip: This retrospective study compares the efficacy of percutaneous mechanical thrombectomy (PMT) and catheter-directed thrombolysis (CDT) in treating acute lower extremity deep venous thrombosis (LEDVT). Results indicate that PMT achieves a comparable thrombus clearance rate to CDT, with significantly lower complication rates, shorter hospital stays, and potentially reduced incidence of post-thrombotic syndrome. The study suggests that PMT offers a safer, more efficient alternative for LEDVT treatment with a notable reduction in the use of urokinase, highlighting its advantages in clinical outcomes and patient care efficiency. Further research is recommended to validate these findings through prospective studies and to explore long-term treatment effects.