Randomized Clinical Trial
Copyright ©The Author(s) 2024.
World J Clin Cases. Jul 16, 2024; 12(20): 4265-4271
Published online Jul 16, 2024. doi: 10.12998/wjcc.v12.i20.4265
Table 1 Comparison of general data between the two groups
Group
n
Age in yr
Height in cm
Weight in kg
Operation time in min
Anesthesia time in min
Intraoperative blood loss in mL
Intraoperative fluid volume in mL
Control group5045.56 ± 6.71160.56 ± 5.2658.23 ± 5.79123.36 ± 14.85125.87 ± 15.66134.12 ± 15.221345.26 ± 74.25
Observation group5046.02 ± 6.34161.04 ± 5.1157.69 ± 6.21121.26 ± 15.07124.78 ± 14.98130.25 ± 16.891331.56 ± 81.02
t        0.3520.4630.4500.7020.3561.2040.881
P value        0.7251.9840.6541.9840.7230.2320.380
Table 2 Comparison of visual simulation rating scores between the two groups
Group
n
4 h after surgery
6 h after surgery
12 h after surgery
24 h after surgery
36 h after surgery
48 h after surgery
Control group502.72 ± 0.563.21 ± 0.473.07 ± 0.413.19 ± 0.372.89 ± 0.412.54 ± 0.36
Observation group502.16 ± 0.412.34 ± 0.382.22 ± 0.392.14 ± 0.342.06 ± 0.321.78 ± 0.31
t        5.70510.178        10.62214.77611.28411.312
P value        0.0000.000        0.0000.0000.0000.000
Table 3 Comparison of sedation scores between the two groups
Group
n
4 h after surgery
6 h after surgery
12 h after surgery
24 h after surgery
36 h after surgery
48 h after surgery
Control group502.73 ± 0.372.39 ± 0.412.01 ± 0.322.05 ± 0.361.97 ± 0.321.35 ± 0.26
Observation group502.74 ± 0.352.32 ± 0.391.96 ± 0.292.02 ± 0.321.92 ± 0.251.33 ± 0.24
t        0.1390.8750.8190.4400.8710.400
P value        0.9000.3840.4150.6610.3860.690
Table 4 Comparison of postoperative recovery indexes between the two groups
n
Get out of bed time in h
Bowel sounds recovery time in h
Anal exhaust in h
Postoperative hospital stay in d
5013.58 ± 3.1416.98 ± 3.8222.36 ± 2.133.89 ± 1.02
5010.41 ± 2.5613.84 ± 2.5918.74 ± 2.253.81 ± 1.14
        5.5334.8118.2620.370
        0.0000.0000.0000.712
Table 5 Comparison of stress-related indicators between the two groups
GroupnCor in nmol/L
Blood sugar in mmol/L
1 d before surgery
6 h after surgery
12 h after surgery
24 h after surgery
1 d before surgery
6 h after surgery
12 h after surgery
24 h after surgery
Control group50285.63 ± 37.14378.59 ± 48.77a492.05 ± 74.63a472.23 ± 67.85a5.12 ± 0.366.15 ± 0.41a7.14 ± 0.45a6.97 ± 0.42a
Observation group50279.93 ± 41.78368.74 ± 45.45a441.74 ± 64.27a389.62 ± 61.04a5.15 ± 0.346.08 ± 0.39a6.61 ± 0.42a6.15 ± 0.35a
t        0.721        1.045        3.612        6.400        0.428        0.875        6.08810.606
P value        0.473        0.299        0.000        0.000        0.669        0.384        0.0000.000
Table 6 Comparison of polysomnography parameters between the two groups
GroupnTST in min
SE, %
1 d before surgery
1 d after surgery
2 d after surgery
1 d before surgery
1 d after surgery
2 d after surgery
Control group50465.25 ± 47.85358.12 ± 31.05a382.02 ± 38.96a96.58 ± 5.0272.26 ± 4.22a82.69 ± 4.91a
Observation group50471.56 ± 42.93389.96 ± 35.22a418.96 ± 42.56a95.23 ± 5.2779.56 ± 4.41a87.16 ± 5.11a
t        0.6944.7954.5271.3124.9814.460
P value        0.4890.0000.0001.9840.0000.000
                REMS, %AI, n/h
Control group5020.85 ± 3.1214.02 ± 2.16a15.89 ± 2.11a1.54 ± 0.484.25 ± 0.63a4.09 ± 0.45a
Observation group5020.79 ± 3.2517.85 ± 2.48a19.08 ± 2.37a1.57 ± 0.453.17 ± 0.55a2.61 ± 0.37a
t        0.0948.2357.1090.3229.13217.963
P value        0.9250.0000.0000.7480.0000.000
Table 7 Comparison of patient-controlled epidural analgesia compressions between the two groups
Group
n
Average number of compressions
Average number of effective compressions
Control group502.02 ± 0.471.88 ± 0.44
Observation group501.83 ± 0.411.75 ± 0.38
t        8.9561.581
P value        0.0000.117