Value of negative pressure sealing drainage on wound healing of Gustilo IIIB and IIIC open fractures

Table 1 General clinical data of the patients

General clinical information		Study group, n = 40	Control group, n = 40	t/²	P value
Sex	Male	36	34	0.457	0.499
	Female	4	6
Mean age in yr		45.90 ± 2.82	45.24 ± 3.05	1.005	0.318
Time between healings in h		6.24 ± 0.95	6.01 ± 0.47	1.432	0.156
Degree of injury	IIIB	23	25	0.208	0.648
	IIIC	17	15
Cause of injury	Crush injuries	13	15	0.365	0.554
	Car accident injuries	16	14
	Machine strangulation	10	16
	Other	1	5

Data are mean ± standard deviation. Control group: Received conventional dressing change; Study group: Received negative pressure closed drainage.

Table 2 Rehabilitation indicators of the patients

Group	Cases	Wound healing time in d	Fracture healing time in d	Length of stay in hospital in d
Study group	40	10.94 ± 0.99	209.41 ± 16.00	16.59 ± 2.78
Control group	40	18.50 ± 3.13	261.96 ± 17.66	24.40 ± 2.68
t	-	14.565	13.947	12.792
P value	-	< 0.001	< 0.001	< 0.001

Data are mean ± standard deviation. Control group: Received conventional dressing change; Study group: Received negative pressure closed drainage.

Table 3 Negative bacterial culture at the wound site during follow-up

Group	Cases	1 mo	2 mo	3 mo
Study group	40	16 (40.00)	28 (70.00)	38 (95.00)
Control group	40	7 (17.50)	19 (47.50)	32 (80.00)
²	-	4.943	4.178	4.114
P value	-	0.026	0.041	0.043

Data are n (%). Control group: Received conventional dressing change; Study group: Received negative pressure closed drainage.

Table 4 Injured limb marks during follow-up

Group	Cases	1 mo	2 mo	3 mo
Study group	40	66.06 ± 4.29	80.72 ± 4.41	87.49 ± 4.38
Control group	40	60.61 ± 4.46	71.54 ± 5.01	80.88 ± 5.39
t	-	5.570	8.699	6.019
P value	-	< 0.001	< 0.001	< 0.001

Data are mean ± standard deviation. Control group: Received conventional dressing change; Study group: Received negative pressure closed drainage.