Clinical Trials Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jul 16, 2024; 12(20): 4199-4205
Published online Jul 16, 2024. doi: 10.12998/wjcc.v12.i20.4199
Value of negative pressure sealing drainage on wound healing of Gustilo IIIB and IIIC open fractures
Bo Fang, Yong-Sheng Wang, Wei Li, Kai Ying, Gang Zong
Bo Fang, Yong-Sheng Wang, Wei Li, Kai Ying, Gang Zong, Department of Trauma Surgery, The Second People’s Hospital of Dalian, Dalian 116019, Liaoning Province, China
Author contributions: Fang B designed the research; Wang YS and Li W conducted the case collection; Ying K and Zong G guided the research.
Institutional review board statement: The research was reviewed and approved by the Review Committee of Fuzhou Medical College of Nanchang University (Approval No. 4445644).
Clinical trial registration statement: This study has not yet been registered with clinical trials.
Informed consent statement: All research participants or their legal guardians provided written informed consent prior to study registration.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No other data are available.
CONSORT 2010 statement: The authors have read the CONSORT 2010 statement, and the manuscript was prepared and revised according to the CONSORT 2010 statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Gang Zong, MBBS, Doctor, Department of Trauma Surgery, The Second People‘s Hospital of Dalian, No. 29 Hongji Street, Xigang District, Dalian 116019, Liaoning Province, China. yingkai1251@163.com
Received: April 8, 2024
Revised: May 10, 2024
Accepted: May 29, 2024
Published online: July 16, 2024
Processing time: 82 Days and 13.3 Hours
Abstract
BACKGROUND

Gustilo III fractures have a high incidence and are difficult to treat. Patients often experience difficulty in wound healing. Negative pressure drainage technology can help shorten wound healing time and has positive value in improving patient prognosis.

AIM

To explore the clinical value of the negative pressure sealing drainage technique in wound healing of Gustilo IIIB and IIIC open fractures.

METHODS

Eighty patients with Gustilo IIIB and IIIC open fractures with skin and soft tissue injuries who were treated in the Second People’s Hospital of Dalian from March 2019 to December 2021 were selected as the research subjects. They were divided into a study group (n = 40, healed with negative pressure closed drainage) and a control group (n = 40, healed with conventional dressing changes) according to the variation in the healing they received. The efficacy of the clinical interventions, the variations in the regression indicators (time to wound healing, time to fracture healing, time to hospitalization), and the conversion and healing of bacterial wounds were compared 1-3 mo after the intervention.

RESULTS

The total effective rate of patients among the study group was 95.00% (38/40), which was notably higher than 75.00% (30/40) among the control group (P < 0.05). The wound healing time, fracture healing time, and hospital stay of the patients in the study group was shorter than the control group (P < 0.05). After the intervention, the negative bacterial culture at the wound site rate and wound healing rate of the patients among the study group increased compared to the control group (P < 0.05).

CONCLUSION

Negative pressure sealing and drainage technology has a good therapeutic effect on patients with Gustilo IIIB and IIIC open fracture wounds with skin and soft tissue injury. It can notably enhance the wound healing rate and the negative rate of bacteria on the wound surface and help to speed up the recovery process of patients.

Keywords: Negative pressure closed drainage, Gustilo type III open fracture, Wound healing, Clinical outcome, Research value

Core Tip: Negative pressure sealing drainage technology can improve the treatment effect of Gustilo IIIB and IIIC open fracture wounds with skin and soft tissue damage. It can accelerate the patient recovery process and improve the wound healing rate.