Therapeutic effect of San Bi Tang combined with glucosamine sulfate capsules in cold-dampness-type knee osteoarthritis

Table 1 Comparison results

Baseline information	CG	TG	Statistical value	P value
Gender (male/female)	18/37	19/36	0.0407	0.8401
Age (yr)	59.63 ± 4.36	59.73 ± 5.01	0.1117	0.9113
Disease course (wk)	49.82 ± 17.95	50.62 ± 16.53	0.2431	0.8084
Stage (early/mid)	37/18	35/20	0.1608	0.6884
Location (left/right)	30/25	25/30	0.9091	0.3404

CG: Control group; TG: Test group.

Table 2 Visual analysis scale scores between two groups of patients [M (P25, P75)]

Group	Before treatment	After treatment	Z	P value
CG	4 (3, 5)	2 (1.25, 2)	3.273	0.002
TG	4 (3, 5)	1 (1, 2)	1.736	0.003
Z	1.959	0.000	-	-
P value	1.001	0.002	-	-

CG: Control group; TG: Test group.

Table 3 Comparison of Western Ontario and McMaster Universities Osteoarthritis Index results

Group	Before treatment	After treatment	Z	P value
CG	29.13 ± 8.40	14.05 ± 3.52	12.267	0.000
TG	27.72 ± 7.26	9.75 ± 3.52	16.518	0.000
t	0.9418	6.4061	-	-
P value	0.3484	0.000	-	-

CG: Control group; TG: Test group.

Table 4 Comparison of 30 s Chair Stand Test results

Group	Before treatment	After treatment	Z	P value
CG	10.89 ± 2.01	12.01 ± 2.21	2.7804	0.003
TG	11.12 ± 2.03	16.01 ± 2.22	12.005	0.000
t	0.597	9.470	-	-
P value	0.275	0.000	-	-

CG: Control group; TG: Test group.

Table 5 Traditional Chinese medicine syndrome results

Group	Before treatment	After treatment	Z	P value
CG	10.89 ± 2.01	12.36 ± 2.21	3.6493	0.000
TG	10.76 ± 2.03	16.01 ± 2.22	12.943	0.000
t	0.3375	8.6414	-	-
P value	0.7364	0.000	-	-

CG: Control group; TG: Test group.

Table 6 The average values of liver and kidney function indicators

Liver and kidney function indicators	Control group			Test group
	Before treatment	After treatment	P value	Before treatment	After treatment	P value
ALT (U/L)	32.23 ± 0.92	32.25 ± 1.03	0.9144	32.23 ± 3.62	33.36 ± 3.25	0.0849
AST (U/L)	29.36 ± 3.26	30.12 ± 2.36	0.1614	23.56 ± 2.35	24.02 ± 2.23	0.2923
ALK (U/L)	85.26 ± 9.23	88.24 ± 8.26	0.2358	86.24 ± 3.56	86.35 ± 2.51	0.8514
GGT (U/L)	36.25 ± 2.34	35.42 ± 2.45	0.069	35.16 ± 3.25	34.32 ± 3.12	0.1667
DBil (μmol/L)	3.26 ± 1.23	3.32 ± 0.25	0.7229	3.36 ± 2.01	3.02 ± 1.03	0.2642
TBil (μmol/L)	5.26 ± 3.25	6.23 ± 2.01	0.0059	6.34 ± 6.12	7.12 ± 5.21	0.4716
TP (g/L)	71.12 ± 1.22	71.23 ± 1.23	0.6377	71.36 ± 2.35	71.86 ± 1.02	0.1492
ALB (g/L)	42.36 ± 1.21	42.53 ± 1.02	0.4256	44.36 ± 2.31	45.26 ± 3.25	0.0942
GLOB (mL/min)	25.46 ± 3.26	26.34 ± 2.12	0.0933	26.34 ± 3.25	27.01 ± 3.21	0.2767
Ccr (mmol/L)	92.36 ± 5.24	93.14 ± 3.24	0.3478	91.02 ± 3.02	92.09 ± 3.26	0.0742
BUN (μmol/L)	6.35 ± 1.02	6.12 ± 1.11	0.2578	7.45 ± 1.85	7.03 ± 1.03	0.1413
UA (μmol/L)	263.26 ± 11.23	271.09 ± 31.02	0.0754	270.01 ± 9.26	272.89 ± 8.12	0.0828

ALT: Alanine transaminase; AST: Aspartate transaminase; ALK: Alkaline phosphatase; GGT: Glutamyltranspeptidase; DBil: Direct bilirubin; TBil: Total bilirubin; TP: Total protein; ALB: Albumin; GLOB: Globulin; Ccr: Creatinine clearance rate; BUN: Blood urea nitrogen; UA: Uric acid.