Magnetic resonance imaging scanning susceptibility weighted imaging sequences in the diagnosis and prognostic evaluation of neonatal hypoxic-ischemic encephalopathy

Table 1 Scanning parameters for magnetic resonance imaging examinations

Imaging format	TR/ms	TE/ms	Field of view (mm)	Layer thickness (mm)
T1WI	2220	22	230 × 230	5
T2WI	640	102	230 × 230	5
FLAIR	7827	170	230 × 230	5
DWI (b = 1000 s/mm2)	4000	94	230 × 230	5
SWI (FA = 15)	49	40	230 × 230	3

T1WI: T1-weighted images; T2WI: T2-weighted images; DWI: Diffusion weighted imaging; SWI: Susceptibility weighted imaging.

Table 2 Comparison of the degree of cerebral edema and brain damage between the two modalities, n (%)

Inspection methods	Hydrocephalus (above moderate, n = 20)	Brain damage to brain regions (> 2, n = 22)	Number of cerebral hemorrhages (> 2, n = 17)
MRI	19 (95.00)	21 (95.45)	16 (94.12)
CT	11 (55.00)	14 (63.63)	8 (47.06)
χ2	8.533	6.844	9.067
P value	< 0.05	< 0.05	< 0.05
Inspection methods	Subventricular hemorrhage	Intraventricular hemorrhage	Intracerebral hemorrhage
	(n = 7)	(n = 5)	(n = 10)
MRI	5 (71.43)	4 (80.00)	9 (90.00)
CT	2 (28.577)	3 (60.00)	5 (50.00)
χ2	2.571	0.476	3.809
P value	> 0.05	> 0.05	> 0.05
Inspection methods	Subarachnoid hemorrhage	Number and extent of cerebral infarctions	Small venous dilatation (medicine)
	(Yes, n = 8)	(> 2, n = 7)	(n = 8)
MRI	7 (87.50)	7 (100.00)	8 (100.00)
CT	8 (100.00)	4 (57.14)	1 (12.50)
χ2	1.067	3.818	12.444
P value	> 0.05	> 0.05	< 0.05

MRI: Magnetic resonance imaging; CT: Computed tomography.

Table 3 Comparison of brain injury and cerebral hemorrhage cut-off area between magnetic resonance imaging and computed tomography scans of neonatal patients with hypoxic-ischemic encephalopathy (mm²)

Inspection method	MRI total area of maximum level of brain damage	Total cerebral hemorrhage in most layers
MRI (n = 23)	14.25 ± 2.31	12.04 ± 1.24
CT (n = 23)	12.14 ± 1.81	10.13 ± 1.02
t	3.448	5.705
P value	0.001	< 0.001

MRI: Magnetic resonance imaging; CT: Computed tomography.

Table 4 Detection of hypoxic-ischemic encephalopathy in newborns by magnetic resonance imaging and computed tomography multi-parameter quantitative indexes

Methodology	Comprehensive clinical judgment		Sum
	Masculine	Negatives
Routine CT
Masculine	12	3	15
Negatives	11	20	31
Sum	23	23	46
Conventional MRI with DWI and SWI
Masculine	21	2	23
Negatives	2	21	23
Sum	23	23	46

DWI: Diffusion weighted imaging; SWI: Susceptibility weighted imaging; MRI: Magnetic resonance imaging; CT: Computed tomography.