Retrospective Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jun 16, 2024; 12(17): 3012-3018
Published online Jun 16, 2024. doi: 10.12998/wjcc.v12.i17.3012
Magnetic resonance imaging scanning susceptibility weighted imaging sequences in the diagnosis and prognostic evaluation of neonatal hypoxic-ischemic encephalopathy
Hui Zhao, Hai-Tao Wang
Hui Zhao, Department of Neonatology, Hanzhong People's Hospital, Hanzhong 723000, Shaanxi Province, China
Hai-Tao Wang, Department of Medical Imaging, Hanzhong People's Hospital, Hanzhong 723000, Shaanxi Province, China
Author contributions: Zhao H and Wang HT, contributed equally to this work; Zhao H designed the research study; Zhao H and Wang HT performed the research; Zhao H and Wang HT analyzed the data and wrote the manuscript; all authors have read and approve the final manuscript.
Institutional review board statement: This study was reviewed and approved by the Ethics Committee of Hanzhong People's Hospital
Informed consent statement: All study participants or their legal guardian provided informed written consent about personal and medical data collection prior to study enrolment.
Conflict-of-interest statement: The authors declare no conflicts of interest for this article.
Data sharing statement: No other available data.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/.
Corresponding author: Hai-Tao Wang, Doctor, Attending Doctor, Department of Medical Imaging, Hanzhong People's Hospital, No. 251 North Tuanjie Street, Hantai District, Hanzhong 723000, Shaanxi Province, China. g8j931@163.com
Received: February 22, 2024
Revised: April 9, 2024
Accepted: April 18, 2024
Published online: June 16, 2024
Processing time: 103 Days and 10.7 Hours
Abstract
BACKGROUND

Magnetic resonance imaging (MRI) scanning with susceptibility weighted imaging (SWI) sequences plays a significant role in the diagnosis and prognostic evaluation of neonatal hypoxic-ischemic encephalopathy (HIE).

AIM

To observe the role of MRI multi-parameter quantitative indexes in the diagnosis of neonatal HIE.

METHODS

The imaging data from 23 cases of neonatal HIE admitted to the Imaging Department of Ganyu District People's Hospital of Lianyungang City and 23 neonates without HIE admitted during the same period were analyzed retrospectively from August, 2021 to December, 2023. The results of clinical judgment were compared with the results of computed tomography (CT) and MRI examinations.

RESULTS

The degree of cerebral edema (more than moderate), the number of damaged brain regions (> 2), the number of cerebral hemorrhages (> 2), and the percentage of small venous dilatation detected were higher in MRI than in CT examination, and the differences were statistically significant (P < 0.05). The total area of the largest region of cerebral damage and of cerebral hemorrhage observed by MRI examination were significantly larger than those of CT examination (P < 0.01). Multiparametric quantitative MRI combined with diffusion weighted imaging and SWI had higher sensitivity and accuracy than CT diagnosis, and the difference was statistically significant (P < 0.05). The difference in the specificity of the two modes of diagnosis was not significant (P > 0.05).

CONCLUSION

The use of MRI multi-parameter quantitative indexes can accurately diagnose and evaluate neonatal HIE.

Keywords: Hypoxic-ischemic encephalopathy; Neonate; Diagnostic efficacy

Core Tip: Susceptibility weighted imaging (SWI) sequences in magnetic resonance imaging scanning potentially provide richer and more detailed imaging information for neonatal hypoxic-ischemic encephalopathy, facilitating early and accurate diagnosis. In prognostic evaluation, SWI reveals pathological changes related to neurological outcomes, providing essential guidance for clinical decision-making and expectations for patient families. However, interpreting SWI images requires integration with clinical manifestations and other imaging indicators to ensure diagnostic accuracy.