Efficacy of incremental loads of cow’s milk as a treatment for lactose malabsorption in Japan

Table 1 Relation between results of the two tests: 200 mL single-blind comparative study and 20 g lactose hydrogen breathe test (LHBT) in LHBT positive subjects (n = 35)

SBCS		Time of abdominal symptom onset during LHBT (min)
Result	n	0	30	60	90	120	150	180	No appearance
Positive	19	1	7	6	1	1	3
Unevaluable	14		9	1	2	1			1
Negative	2		1						1
Total	35	1	17	7	3	2	3		2

SBCS: 200 mL single-blind comparative study. LHBT: 20 g lactose hydrogen breathe test. Positive: More obvious symptoms induced by general milk than by lactose-reduced milk. Unevaluable: Symptoms induced by lactose-reduced milk, or unclear difference between the two materials. Negative: No symptoms induced by either material. LHBT: Lactose hydrogen breathe test; SBCS: Single-blind comparative study.

Table 2 Relation between results of the two tests: 200 mL single-blind comparative study and 20 g lactose hydrogen breathe test (LHBT) in LHBT negative subjects (n = 11)

SBCS		Time when symptoms appeared during LHBT (min)
Result	n	0	30	60	90	120	150	180	No appearance
Positive	3		1		1				1
Unevaluable	6		5						1
Negative	2				1				1
Total	11		6		2				3

SBCS: 200 mL single-blind comparative study. LHBT: 20 g lactose hydrogen breathe test. Positive: More obvious symptoms induced by general milk than by lactose-reduced milk. Unevaluable: Symptoms induced by lactose-reduced milk, or unclear difference between the two materials. Negative: No symptoms induced by either material. LHBT: Lactose hydrogen breathe test; SBCS: Single-blind comparative study.