Selective laser trabeculoplasty as adjunctive treatment for open-angle glaucoma vs following incisional glaucoma surgery in Chinese eyes

Table 1 Demographic and clinical characteristics of patients

Characteristics
Age (yr, mean ± SD)	44.34 ± 16.14
Gender
Male (n)	33 (3 both eyes)
Female (n)	37 (2 both eyes)
Diagnosis
OAG (n)	36
PGS (n)	39
Total	75

OAG: Open angle glaucoma; PGS: Prior glaucoma surgery.

Table 2 Type of prior glaucoma surgery group

Type of PGS	Trabeculectomy	Drainage nail implantation	Ahmed glaucoma valve implantation	Trabeculectomy combined with cataract extraction
Number of patients	18	2	4	15

PGS: Prior glaucoma surgery.

Table 3 Evaluation of intraocular pressures and cumulative proportion of selective laser trabeculoplasty success

Groups	Baseline	1 d	1 wk	1 mo	3 mo	6 mo	12 mo	36 mo
Eyes (n)	36	36	36	36	36	36	35	28
OAG	22.75 ± 2.08	16.29 ± 3.62	18.97 ± 5.42	18.62 ± 4.39	21.32 ± 2.19	22.59 ± 2.26	20.13 ± 1.8	20.73 ± 1.82
P1 value		< 0.0001	0.0005	0.0005	0.0020	0.3465	< 0.0001	0.0009
Cumulative proportion of SLT success (%)				87.13	76.81	68.27	47.66	24.96
Eyes (n)	39	39	39	39	39	39	33	29
PGS	22.52 ± 2.62	16.45 ± 4.16	18.51 ± 5.09	18.80 ± 4.99	19.21 ± 3.82	21.94 ± 2.11	20.28 ± 1.61	20.49 ± 1.53
P1 value		< 0.0001	0.0002	0.0002	0.0002	0.3086	< 0.0001	0.0002
Cumulative proportion of SLT success (%)				84.70	67.40	59.39	42.15	27.61
P2 value	0.517	0.785	0.517	0.696	0.006	0.433	0.987	0.594

OAG: Open-angle glaucoma; SLT: Selective laser trabeculoplasty; PGS: Prior glaucoma surgery. P1: Repetitive measure analysis of variance (ANOVA), difference of intraocular pressures (IOP) between selective laser trabeculoplasty treatment and baseline group at different time points. P2: One way ANOVA, Comparison within groups, difference of IOP between open angle glaucoma and prior glaucoma surgery groups at different time points.

Table 4 Number of glaucoma medications used in patients undergoing selective laser trabeculoplasty

Number of medications	Baseline	1 d	1 wk	1 mo	3 mo	6 mo	12 mo	36 mo
OAG	3.39 ± 0.69	3.31 ± 0.82	2.75 ± 0.5	2.06 ± 0.79	2.19 ± 0.71	2.39 ± 0.64	2.34 ± 0.64	2.5 ± 0.69
P1 value		0.083	< 0.001	< 0.001	< 0.001	< 0.001	< 0.001	< 0.001
PGS	2.97 ± 0.74	2.85 ± 0.67	2.51 ± 0.56	1.33 ± 1.28	1.44 ± 1.23	1.77 ± 0.99	1.79 ± 1.02	1.9 ± 0.82
P1 value		0.025	< 0.001	< 0.001	< 0.001	< 0.001	< 0.001	< 0.001
P2 value	0.015	0.005	0.048	0.004	0.003	0.006	0.008	0.007

OAG: Open angle glaucoma; PGS: Prior glaucoma surgery. P1: Wilcoxon signed rank test, difference of medication quantity between selective laser trabeculoplasty treatment and baseline group at different time points. P2: Mann-Whitney test, Comparison within groups, difference of medication quantity between open angle glaucoma and prior glaucoma surgery group at different time points.