Zhu J, Guo J. Selective laser trabeculoplasty as adjunctive treatment for open-angle glaucoma vs following incisional glaucoma surgery in Chinese eyes. World J Clin Cases 2023; 11(4): 780-787 [PMID: 36818631 DOI: 10.12998/wjcc.v11.i4.780]
Corresponding Author of This Article
Juan Guo, MD, Chief Physician, Doctor, Department of Ophthalmology, The Third People's Hospital of Chengdu, Affiliated Hospital of Southwest Jiao Tong University, Affiliated Chengdu Second Clinical College of Chongqing Medical University, NO. 82, Qing Long Street, Chengdu 610031, Sichuan Province, China. guojuan869@163.com
Research Domain of This Article
Ophthalmology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Feb 6, 2023; 11(4): 780-787 Published online Feb 6, 2023. doi: 10.12998/wjcc.v11.i4.780
Selective laser trabeculoplasty as adjunctive treatment for open-angle glaucoma vs following incisional glaucoma surgery in Chinese eyes
Jing Zhu, Juan Guo
Jing Zhu, Juan Guo, Department of Ophthalmology, The Third People's Hospital of Chengdu, Affiliated Hospital of Southwest Jiao Tong University, Affiliated Chengdu Second Clinical College of Chongqing Medical University, Chengdu 610031, Sichuan Province, China
Author contributions: Zhu J collected and analyzed the data; Guo J conceived and supervised the project; All authors have read and approved the article.
Supported byNatural Science Foundation of Sichuan Province of China, No. 2022NSFSC1400, and Youth Innovation Project of Sichuan Medical Association, No. Q15045.
Institutional review board statement: The study was reviewed and approved by the Third People’s Hospital of Chengdu Institutional Review Board (Approval No. [2022]-S-5).
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: The authors have no conflict of interest to declare. The authors alone are responsible for the content and writing of the paper.
Data sharing statement: The data that support the findings of this study are available on request from the corresponding author.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Juan Guo, MD, Chief Physician, Doctor, Department of Ophthalmology, The Third People's Hospital of Chengdu, Affiliated Hospital of Southwest Jiao Tong University, Affiliated Chengdu Second Clinical College of Chongqing Medical University, NO. 82, Qing Long Street, Chengdu 610031, Sichuan Province, China. guojuan869@163.com
Received: October 15, 2022 Peer-review started: October 15, 2022 First decision: November 16, 2022 Revised: November 30, 2022 Accepted: January 9, 2023 Article in press: January 9, 2023 Published online: February 6, 2023 Processing time: 113 Days and 16.2 Hours
Abstract
BACKGROUND
Selective laser trabeculoplasty (SLT) is a relatively safe and effective therapy in lowering intraocular pressures (IOP) for glaucoma.
AIM
To study the long-term effects of SLT on IOP and number of glaucoma medications used in Chinese eyes.
METHODS
This is a retrospective study in which 75 eyes of 70 patients with open-angle glaucoma (OAG, n =36) and eyes with prior glaucoma surgery (PGS, n =39) were included. Changes in mean IOP and number of glaucoma medications used evaluated at 1 d, 1 wk, 1 mo, 3 mo, 6 mo, 12 mo, and 36 mo after laser treatment.
RESULTS
All patients (33 male, 37 female) were Chinese. The mean age was 44.34 ± 16.14 years. Mean pre-SLT IOP was 22.75 ± 2.08 mmHg in OAG and 22.52 ± 2.62 mmHg in PGS. Mean IOP was significantly reduced 1 d, 1 wk, 1 mo and 3 mo after laser treatment (P < 0.05, respectively). Whereas, there were no significant differences between baseline and SLT treated groups at the 6th month both in OAG (P = 0.347, P > 0.05) and in PGS (P = 0.309, P > 0.05). Six months after SLT treatment, some patients received retreatment of SLT or were given more topical IOP-lowering medication to control the IOP. By the end of our study, the average IOP decreased to 20.73 ± 1.82 mmHg in OAG and 20.49 ± 1.53 mmHg in PGS groups. The number of glaucoma medications used was significantly reduced until the end of 3 years compared to baseline.
CONCLUSION
SLT could reduce IOP as adjunctive treatment both in OAG and PGS groups. SLT significantly reduced the number of glaucoma medications used 3-years following treatment in glaucoma patients.
Core Tip: Selective laser trabeculoplasty (SLT) could reduce intraocular pressure as adjunctive treatment both in open-angle glaucoma and prior glaucoma surgery groups of patients. SLT significantly reduced the number of glaucoma medications used 3-years following treatment in glaucoma patients.
