Mendelian randomization provides evidence for a causal effect of serum insulin-like growth factor family concentration on risk of atrial fibrillation

doi:10.12998/wjcc.v11.i36.8475

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Evidence-Based Medicine

World J Clin Cases. Dec 26, 2023; 11(36): 8475-8485
Published online Dec 26, 2023. doi: 10.12998/wjcc.v11.i36.8475

Table 1 All genome-wide association study datasets selected in this article

Trait	GWAS id	Sample size	Number of SNPs
Atrial Fibrillation	ebi-a-GCST006414	1030836	33519037
Atrial Fibrillation	ukb-b-536	337199	10894596
Atrial Fibrillation	finn-b-I9_AF	-	16379794
IGF-1	prot-c-2952_75_2	-	501428
IGF-I sR	prot-c-4232_19_2	-	501428
IGF-IIR	prot-c-3676_15_3	-	501428
IGFBP-1	prot-c-2771_35_2	-	501428
IGFBP-2	prot-c-2570_72_5	-	501428
IGFBP-3	prot-c-2571_12_3	-	501428
IGFBP-4	prot-c-2950_57_2	-	501428
IGFBP-5	prot-c-2685_21_2	-	501428
IGFBP-6	prot-c-2686_67_2	-	501428
IGFBP-7	prot-c-3320_49_2	-	501428
IGF-LR1	prot-a-1455	3301	10534735
CTGF	prot-c-2975_19_2	-	501428
WISP-1	prot-c-3057_55_1	-	501428
CYR61	prot-a-758	3301	10534735

GWAS: Genome-wide association study; SNPs: Single nucleotide polymorphisms.

Citation: Lin S, Tang J, Li X, Wu G, Lin YF, Li YF. Mendelian randomization provides evidence for a causal effect of serum insulin-like growth factor family concentration on risk of atrial fibrillation. World J Clin Cases 2023; 11(36): 8475-8485
URL: https://www.wjgnet.com/2307-8960/full/v11/i36/8475.htm
DOI: https://dx.doi.org/10.12998/wjcc.v11.i36.8475