Multiple disciplinary team management of rare primary splenic malignancy: Two case reports

Table 1 The immunohistochemical markers of angiosarcoma, histiocytic sarcoma, and reported cases

Immunohistochemical markers	AS	HS	Case 1	Case 2
CD4		Positive	∕	Positive
Lysozyme	Positive	Positive	Positive	Positive
CD45		Positive	∕	Positive
CD31	Positive	Positive	Positive	Positive
ERG	Positive		Positive	Negative
CD34	Positive		Positive	Negative
CD68	Positive	Positive	Focally positive	Positive
CD163		Positive	∕	Negative
CD8			Positive	Negative
S-100		Positive	Negative	Negative
CD21			∕	Negative
CK	Positive		∕	Negative
F8	Positive	Positive	Positive	∕
SMA	Positive		Positive	∕
Sox-10			Negative	∕
Ki-67			Positive, 5%-10%	Positive, 15%-20%
P53			Positive	Negative

AS: Angiosarcoma; SMA: Smooth muscle actin; ERG: Erythroblast transformation specific related gene; HS: Histiocytic sarcoma.