Case Report
Copyright ©The Author(s) 2022.
World J Clin Cases. Sep 26, 2022; 10(27): 9911-9920
Published online Sep 26, 2022. doi: 10.12998/wjcc.v10.i27.9911
Table 1 Routine laboratory examination of the patient, taken in a state of hemorrhagic shock
Parameter (units)Measured valueNormal value
White blood cell (109/L)12.93.6-8.9
Neu (%)83.437-72
Lym (%)13.425-48
Mon (%)2.62-12
Eos (%)0.41-9
Bas (%)0.20-2
Red blood cell (1012/L)3.133.8-5.04
Platelet (109/L)221153-346
Aspartate transaminase (IU/L)145-37
Alanine aminotransferase (IU/L)126-43
Lactic acid dehydrogenase (IU/L)164119-221
Alkaline phosphatase (IU/L)159110-348
Gamma-glutamyl transpeptidase (IU/L)150-75
Total bilirubin (mg/dL)0.50.4-1.2
Total protein (g/dL)7.46.5-8.5
Albumin (g/dL)4.53.8-5.2
Creatine kinase (U/L)9547-200
Blood urea nitrogen (mg/dL)139-21
Creatinine (mg/dL)0.760.5-0.8
Amylase (IU/L)9843-124
Sodium (mEq/L)140135-145
Potassium (mEq/L)3.33.5-5
Chloride (mEq/L)11096-107
C-reactive protein (mg/dL)0.030-0.29
Plasma glucose (mg/dL)15665-109
Activated partial thromboplastin time (Seconds)24.823-36
Prothrombin time-international normalized ratio1.10.85-1.15
D-dimer (μg/mL)1.10-1
Table 2 Summary of prior reported cases of esophageal submucosal hematoma
Case No.
Underlying disease
Antiplatelet therapy
Anticoagulation therapy
Imaging findings
Prognosis time
1199864MIschemic heart diseaseNoneNoneRetrostemal pain and coffee-ground vomitusCT: A non-enhancing low-density submucosal columnar lesion in the mid- and lower oesophagus consistent with a submucosal haematoma. MRI: Intermediate signal intensity on T1-weighted images and hyperintense signal on T2-weighted images of this lesion.NoneRecoveredN/AYuen et al[9]
2200067MUnruptured cerebral aneurysmNoneHeparinHematemesisCT: A longitudinal water density mass without enhancement in the distal half of the esophageal lumen. It extended from about 3 cm below the level of the tracheal carina to the esophagocardiac junction.NoneRecoveredN/AYamashita et al[10]
3200184FDissecting aortic aneurysm NoneNoneChest discomfort and hematemesisCT: Partial thickness of the esophageal wall which was not enhanced by contrast medium.NoneRecoveredN/AKise et al[11]
4201068FCerebrovascular diseaseANoneHematemesis and retrostemal painNoneNoneRecoveredN/AZimmer et al[12]
5201332FNeurofibromatosis type 1NoneNoneSever central chest pain and interscapular pain associated with dysphagia N/AMassive bleeding with hypovolemic shock due to dissecting intramural hematoma of the esophagusDead6 hoursPomara et al[13]
6201474MCerebral infarction and chronic hepatitis CANoneHematemesisNoneNoneRecoveredN/AOe et al[2]
7201670F Unruptured cerebral aneurysmAHeparinEpigastric pain and nauseaUnknownUnknownRecoveredN/AFujimoto et al[7]
8201781M Idiopathic thrombocytopenic purpuraNoneNoneChest pain and dysphagiaCT: A 17-cm long segment of homogeneous, soft tissue like density in the mid-to-distal esophagus with smooth eccentric configuration causing luminal narrowing. The maximal esophageal wall measures approximately 26 mm in thickness. Upper gastrointestinal contrast study: A large eccentric luminal narrowing caused by a mural wall compression of the mid-to-distal esophagus, confirming the submucosal hematoma.NoneRecoveredN/ASharma et al[14]
9201785F Atrial fibrillation NoneDabigatranHemoptysisUnknownUnknownRecoveredN/ATrip et al[15]
10201775F Unruptured cerebral aneurysmA+C Heparin + ArgatrobanHematemesisCT: Dilatation of the entire esophagus and the soft tissue shadow filled on the dorsal side that was ventrally displacing the lumen.NoneRecoveredN/AIto et al[16]
11201965F Unruptured cerebral aneurysmAHeparinHematemesisUnknownUnknownRecoveredN/AFujii et al[5]
12201973F Unruptured cerebral aneurysmA+C HeparinEpigastric pain and hematemesisUnknownUnknownRecoveredN/AFujii et al[5]
13201965F Unruptured cerebral aneurysmA+C HeparinEpigastric painUnknownUnknownRecoveredN/AFujii et al[5]
14202073F Unruptured cerebral aneurysmA+C HeparinHematemesisCT: A dilatation from the middle to lower esophagus, and that the esophageal lumen was almost entirely filled with hematomas. An occupying lesion with a relatively clear boundary was observed under the mucosa at the esophagogastric junction, which had partial contrast effects.NoneRecoveredN/AN/A

  • Citation: Oba J, Usuda D, Tsuge S, Sakurai R, Kawai K, Matsubara S, Tanaka R, Suzuki M, Takano H, Shimozawa S, Hotchi Y, Usami K, Tokunaga S, Osugi I, Katou R, Ito S, Mishima K, Kondo A, Mizuno K, Takami H, Komatsu T, Nomura T, Sugita M. Hemorrhagic shock due to submucosal esophageal hematoma along with mallory-weiss syndrome: A case report. World J Clin Cases 2022; 10(27): 9911-9920
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