Evaluation of the prognostic nutritional index for the prognosis of Chinese patients with high/extremely high-risk prostate cancer after radical prostatectomy

Table 1 Composition of high prognostic nutritional index and low prognostic nutritional index in population with different clinical features

		n	PNI (n = 193)		χ2	P value
			≤ 46.23 (n = 108), n (%)	> 46.23 (n = 85), n (%)
Age	≤ 65	69	43 (62.3)	26 (37.7)	0.078	0.779
	> 65	124	65 (52.4)	59 (47.6)
Chronic disease	Find	122	68 (55.7)	54 (44.3)	0.007	0.935
	Nil	71	40 (56.3)	31 (43.7)
Margin status	Positivity	64	35 (54.7)	29 (45.3)	0.063	0.802
	Feminine	129	73 (56.6)	56 (43.4)
Envelope violations	Yes	59	29 (49.2)	30 (50.8)	1.597	0.206
	No	134	79 (59.0)	55 (41.0)
Postoperative adjuvant therapy	Find	173	101 (58.4)	72 (41.6)	1.310	0.252
	Nil	20	7 (35.0)	13 (65.0)
Nerve invasion	Yes	105	62 (59.0)	43 (41.0)	0.892	0.345
	No	88	46 (52.3)	42 (47.7)

PNI: Prognostic nutritional index.

Table 2 Postoperative complications in high prognostic nutritional index group and low prognostic nutritional index group

	n	PNI		χ2	P value
		≤ 46.23, n (%)	> 46.23, n (%)
Postoperative complication	59	41 (38.96)	18 (21.18)	6.315	0.012
Incision infection	8	6	2
Postoperative bleeding	8	4	4
Abdominal infection	7	6	1
Rectal injury	5	3	2
Postoperative penile erectile dysfunction	7	4	3
Permanent/temporary urinary incontinence	0	0	0
Bladder-urethral anastomotic stenosis	6	4	2
Urethral stricture	8	7	1
Deep venous thrombosis	0	0	0
Lymphatic cyst	3	2	1
Urinary fistula	9	4	5
Pulmonary embolism	6	2	4

PNI: Prognostic nutritional index.

Table 3 Cox proportional hazards regression model of influencing factors of biological recurrence in patients

	Parameter estimation	Standard error	HR (95%CI)	P value
PNI, 0: > 46.23; 1: ≤ 46.23	0.61	0.27	1.74 (1.03-2.85)	0.003
Age, 0: ≤ 65; 1: > 65	0.27	0.16	1.31 (0.95-1.80)	0.102
Chronic disease, 0: Nil; 1: Find	0.35	0.22	1.41 (0.92-2.18)	0.120
Margin status, 0: Feminine; 1: Positivity	0.71	0.28	2.14 (1.22-3.62)	0.001
Envelope violations, 0: No; 1: Yes	0.17	0.10	1.08 (0.88-1.32)	0.473
Nerve invasion, 0: No; 1: Yes	0.44	0.31	1.59 (0.86-2.96)	0.147
Postoperative adjuvant therapy, 0: Nil; 1: Find	-0.11	0.18	0.90 (0.63-1.28)	0.548

CI: Confidence interval; HR: Hazard ratio; PNI: Prognostic nutritional index.