Clinical significance of half-hepatic blood flow occlusion technology in patients with hepatocellular carcinoma with cirrhosis

Table 1 Comparison of baseline data between the two groups of patients, n (%)

Normal information	Research group (n = 44)	Control group (n = 44)	t/χ2 value	P value
Age (yr)	60.6 ± 5.0	61.3 ± 5.5	-0.625	0.534
Lesion diameter (cm)	5.18 ± 1.00	5.08 ± 1.30	0.404	0.687
Serum AFP (ng/L)	240.8 ± 75.6	228.6 ± 66.3	0.805	0.423
Sex			0.733	0.392
Male	26 (59.09)	22 (50.00)
Female	18 (40.91)	22 (50.00)
Child-Pugh stage			1.252	0.263
A stage	40 (100)	37 (84.09)
B stage	4 (9.09)	7 (15.91)
Hepatitis B virus infection			1.286	0.257
Yes	32 (72.73)	27 (61.36)
No	12 (27.27)	17 (38.64)
Surgical resection range			0.786	0.375
≥ 3 liver segments	18 (40.91)	14 (31.82)
< 3 liver segments	26 (59.09)	30 (68.18)

Table 2 Comparison of surgical process indicators between the two groups (mean ± SD)

Index	Research group (n = 44)	Control group (n = 44)	t value	P value
Operation time (min)	273.0 ± 24.8	256.3 ± 28.5	2.932	0.004
Incision length (cm)	25.98 ± 1.55	26.14 ± 1.64	-0.470	0.639
Surgical bleeding (mL)	626.9 ± 105.1	598.4 ± 97.0	1.322	0.190
Portal block time (min)	25.3 ± 4.1	23.5 ± 4.5	1.961	0.053
Postoperative anal exhaust time (h)	50.0 ± 9.7	55.1 ± 10.4	-2.379	0.020
Drainage tube indwelling time (d)	3.84 ± 0.66	3.62 ± 0.71	1.505	0.136
Hospital stay (d)	13.6 ± 1.8	14.0 ± 2.2	-0.933	0.353

Table 3 Comparison of liver function indexes between the two groups of patients (mean ± SD)

Index	Research group (n = 44)	Control group (n = 44)	t value	P value
ALT (U/L)
Preoperative	33.04 ± 8.56	34.72 ± 8.11	-0.945	0.347
24 h after operation	378.61 ± 77.49a	430.58 ± 83.67a	-3.023	0.003
72 h after operation	246.13 ± 54.06a	281.35 ± 59.61a	-2.903	0.005
AST (U/L)
Preoperative	29.61 ± 7.21	27.30 ± 7.85	1.438	0.154
24 h after operation	355.30 ± 69.50a	416.49 ± 73.03a	-4.026	0.000
72 h after operation	223.47 ± 48.64a	248.62 ± 50.10a	-2.389	0.019
TBIL (μmol/L)
Preoperative	15.92 ± 4.40	15.28 ± 4.71	0.659	0.512
24 h after operation	32.85 ± 7.01a	34.06 ± 8.43a	-0.732	0.466
72 h after operation	20.46 ± 5.83a	22.90 ± 6.15a	-1.910	0.059
PA (mg/dL)
Preoperative	313.86 ± 46.91	320.74 ± 51.67	-0.654	0.515
24 h after operation	194.82 ± 32.65a	188.57 ± 29.48a	0.942	0.349
72 h after operation	275.12 ± 41.81a	269.84 ± 46.10a	0.563	0.575

^aP < 0.05 vs this group before surgery.

ALT: Alanine transaminase; AST: Aspartate aminotransferase; TBIL: Total bilirubin; PA: Prealbumin.

Table 4 Comparison of tumor marker levels between the two groups (mean ± SD)

Index	Research group (n = 44)	Control group (n = 44)	t value	P value
AFU (U/L)
Preoperative	66.41 ± 9.51	68.18 ± 10.84	-0.814	0.418
1 mo after operation	27.04 ± 6.44a	29.95 ± 8.27a	-1.842	0.069
AFP (ng/L)
Preoperative	240.8 ± 75.6	228.6 ± 66.3	0.805	0.423
1 mo after operation	78.55 ± 18.04a	82.01 ± 20.63a	-0.837	0.405
CEA (μg/L)
Preoperative	18.58 ± 4.20	20.03 ± 4.81	-1.506	0.136
1 mo after operation	3.77 ± 0.89a	4.01 ± 0.81a	-1.323	0.189

^aP < 0.05 vs this group before surgery.

AFU: Alpha-L fasosylase; AFP: Alpha-fetoprotein; CEA: Carcinoembryonic antigen.

Table 5 Comparison of inflammatory factors between the two groups of patients before and after surgery (mean ± SD)

Index	Research group (n = 44)	Control group (n = 44)	t value	P value
IL-6 (pg/mL)
Preoperative	54.23 ± 9.50	56.39 ± 9.11	-1.089	0.279
24 h after operation	97.41 ± 17.59	108.26 ± 18.25	-2.839	0.006
72 h after operation	70.55 ± 13.02	74.18 ± 14.40	-1.240	0.218
TNF-α (pg/mL)
Preoperative	68.33 ± 13.20	70.53 ± 12.65	-0.798	0.427
24 h after operation	148.12 ± 21.04	167.00 ± 24.28	-3.898	0.000
72 h after operation	98.40 ± 13.27	102.73 ± 15.19	-1.424	0.158
CRP (mg/L)
Preoperative	4.91 ± 1.53	5.34 ± 1.58	-1.297	0.198
24 h after operation	18.48 ± 3.75	20.14 ± 4.43	-1.897	0.061
72 h after operation	14.20 ± 3.36	15.38 ± 4.28	-1.438	0.154

IL-6: interleukin-6; TNF-α: tumor necrosis factor-α; CRP: C-reactive protein.