Extranasopharyngeal angiofibroma in children: A case report

Table 1 Characteristics of extranasopharyngeal angiofibromas in children

No	Ref.	Site of origin	Age	Sex
1	Munson[21], 1941	Maxillary sinus	15 years	M
2	Radcliffe[22], 1951	Ethmoid sinus	16 years	M
3	Alajmo and Fini-Storchi[26], 1962	Maxillary sinus	9 years	M
4	Whitlock et al[23], 1961	Cheek	16 years	M
5	Alajmo and Fini-Storchi[26], 1962	Maxillary sinus	6 years	M
6	Hora and Brown[26], 1962	Maxillary sinus	13 years	M
7	Furstenborg and Boles[26], 1963	Ethmoid sinus	1 months	M
8	Minicone[26], 1964	Conjunctiva	17 years	M
9	Ogura[26], 1965	Maxillary sinus	16 years	M
10	Chaikovskii[26], 1967	External nose	14 years	F
11	Szczepanski et al[24], 1967	Ethmoid sinus	13 years	F
12	Manigla[26], 1969	Maxillary sinus	15 years	M
13	Pathak[26], 1970	Maxillary sinus	18 years	M
14	Beeden and Alexander[26], 1971	Oropharynx and hypopharynx	1 years	M
15	Charkabti[26], 1973	Maxillary sinus	17 years	M
16	Rye[26],1973	Maxillary sinus	17 years	M
17	Stewart and O’Brien[26], 1973	Molar and retromolar	10 years	M
18	Ramajaneyulu[26], 1974	Maxillary sinus	17 years	M
19	Yamagiwa[26], 1974	Sphenoid sinus	14 years	M
20	Isherwood et al[25], 1975	Pterygomaxillary fissure, infratemporal region	13 years	M
21	Krutchkoff[30], 1977	Maxillary sinus	12 years	M
22	Reddy[26], 1979	Molar and retromolar area	14 years	F
23	Obiako et al[31], 1983	Roof of nasal cavity	12 years	M
24	Hiraide and Matsubara[27], 1984	Nasal septum	13 years	M
25	Sarpa and Novelly[28], 1989	Nasal septum	9 years	M
26	Kitano et al[32], 1992	Maxillary sinus	13 years	M
27	Manjalay et al[33], 1992	Maxillary sinus	Newborn	M
28	Gaffney et al[18], 1997	Inferior turbinate	9 years	M
29	Schick et al[6], 1997	Lacrimal sac	15 months	M
30	Schick et al[6], 1997	Paranasal sinus	9 years	M
31	Schick et al[6], 1997	Sphenoid sinus	6 years	M
32	Huang et al[8], 2000	Middle turbinate	14 years	M
33	Handa et al[12], 2001	Nasal septum	8 years	M
34	Panesar et al[2], 2003	Maxillary sinus	1 years	M
35	Gupta et al[34], 2006	Infratemporal region	13 years	M
36	Castillo et al[29], 2006	Nasal septum	9 years	M
37	Ifeacho and Caulfield[35], 2011	Middle turbinate	14 years	M
38	Singhal et al[17], 2014	Nasal septum	12 years	M
39	Ganguly et al[16], 2017	Nasal septum	7 years	M
40	Singh et al[17], 2018	Nasal septum	9 years	F
41	Kim et al[20], 2019	Inferior turbinate	9 years	M
42	Kim et al[20], 2019	Inferior turbinate	16 years	M
43	Kim et al[20], 2019	Inferior turbinate	8 years	F
44	Kim et al[20], 2019	Inferior turbinate	12 years	F
45	Our case	Inferior turbinate and lateral wall of nasopharynx	4 years	M

Table 2 Reported cases of extranasopharyngeal angiofibroma in children (n = 45)

Variable	N (%)
Gender
Male	39 (86.7%)
Female	6 (13.3%)
Age at the time of surgery
≤ 6 years	8 (17.8%)
7-12 years	15 (33.3%)
13-18 years	22 (48.9%)
Site
Maxillary sinus	15 (33.3%)
Ethmoid sinus	3 (6.7%)
Sphenoid sinus	2 (4.4%)
Nasal septum	7 (15.6%)
Inferior turbinate	6 (13.3%)
Middle turbinate	2 (4.4%)
Roof of nasal cavity	1 (2.2%)
Lacrimal sac	1 (2.2%)
Cheek	1 (2.2%)
Conjunctiva	1 (2.2%)
External nose	1 (2.2%)
Molar and retromolar area	2 (4.4%)
Oropharynx and hypopharynx	1 (2.2%)
Infratemporal region	2 (4.4%)